Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | CCR6 | P51684 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 5/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.42 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11800210 | 0.83 | TSHR (0.39) | TDP1CYP1A2TSHRCYP3A4GPR35 | |
| SCHEMBL10797402 | 0.81 | TSHR (0.50) | TDP1CYP1A2TSHRCYP3A4GPR35 | |
| SCHEMBL5078794 | 0.81 | GPR35 (0.61) | TDP1CYP1A2GPR35ALDH1A1CYP2C9 | |
| SCHEMBL31212653 | 0.79 | AKR1C3 (0.45) | TDP1CCR6CYP1A2TSHRGPR35 | |
| SCHEMBL2436243 | 0.78 | TSHR (0.56) | TDP1TSHRCYP3A4SMN1; SMN2ALDH1A1 | |
| SCHEMBL11575207 | 0.78 | CYP1A2 (0.44) | TDP1CYP1A2CYP3A4SMN1; SMN2ALDH1A1 | |
| SCHEMBL689130 | 0.78 | TPMT (0.46) | TDP1TSHRCYP3A4ALDH1A1HSD17B10 | |
| SCHEMBL4547845 | 0.77 | TSHR (0.55) | TDP1CYP1A2TSHRCYP3A4GPR35 | |
| SCHEMBL260768 | 0.77 | GPR35 (0.67) | TDP1CCR6CYP1A2TSHRCYP3A4 | |
| SCHEMBL11574717 | 0.76 | CYP1A2 (0.50) | TDP1CYP1A2CYP3A4SMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7351513-B2 | Planographic printing plate precursor, substrate for the same and surface hydrophilic material | FUJIFILM CORPORATION (JP) | 2008-04-01 | — | — | US | disclosed |
| US-20080071054-A1 | Planographic printing plate precursor, substrate for the same and surface hydrophilic material | FUJIFILM CORPORATION (JP) | 2008-03-20 | — | — | US | disclosed |
| EP-0887346-B1 | N-Phenyl-alkylsulfonamide derivatives, their preparation and their use as alpha1A/1L adrenoceptor agonists | HOFFMANN LA ROCHE (CH) | 2007-12-12 | — | — | EP | disclosed |
| US-7306850-B2 | Planographic printing plate precursor, substrate for the same and surface hydrophilic material | FUJIFILM CORPORATION (JP) | 2007-12-11 | — | — | US | disclosed |
| US-7273691-B2 | Planographic printing plate precursor, substrate for the same and surface hydrophilic material | FUJIFILM CORPORATION (JP) | 2007-09-25 | — | — | US | disclosed |
| US-20070122745-A1 | Planographic printing plate precursor, substrate for the same and surface hydrophilic material | FUJI PHOTO FILM CO., LTD. (JP) | 2007-05-31 | — | — | US | disclosed |
| US-6057349-A | ALPHA.SUB.1A/1L AGONISTS USED IN THE TREATMENT OF VARIOUS DISEASE STATES SUCH AS URINARY INCONTINENCE, NASAL CONGESTION, PRIAPISM, DEPRESSION, ANXIETY, DEMENTIA, SENILITY, ALZHEIMER'S, DEFICIENCIES IN ATTENTIVENESS AND COGNITION, AND | F. HOFFMAN LA ROCHE AG (CH) | 2000-05-02 | — | — | US | disclosed |
| US-5952362-A | INHIBITOR OF GLYCOGEN PHOSPHORYLASE ENZYMETIC ACTIVITY AND GLUCOSE ACITIVITY | SYNTEX (U.S.A) INC. (US) | 1999-09-14 | — | — | US | disclosed |
| EP-0887346-A2 | Phenyl-and aminophenyl-alkylsulfonamide and urea derivatives, their preparation and their use as alpha1A/1L adrenoceptor agonists | F. HOFFMANN-LA ROCHE AG (CH) | 1998-12-30 | — | — | EP | disclosed |