Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | F10 | P00742 | 1/20 | 0.36 |
| ▸ | JMJD7 | P0C870 | 1/20 | 0.36 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | HTR6 | P50406 | 1/20 | 0.36 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.36 |
| ▸ | TTR | P02766 | 1/20 | 0.36 |
| ▸ | PPOX | P50336 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5205566 | 1.00 | TDP1 (0.41) | TDP1TBXA2RLMNAMAPTMEN1 | |
| SCHEMBL5206332 | 0.84 | ALOX5 (0.44) | MEN1KMT2AALOX5P2RX4PTGER4 | |
| SCHEMBL6175334 | 0.80 | PTGER4 (0.47) | TDP1TBXA2RLMNAMAPTMEN1 | |
| SCHEMBL6177071 | 0.80 | PTGER4 (0.47) | TDP1TBXA2RLMNAMAPTMEN1 | |
| SCHEMBL6175825 | 0.80 | PTGER4 (0.47) | TDP1TBXA2RLMNAMAPTMEN1 | |
| SCHEMBL3717712 | 0.79 | ALOX5 (0.42) | LMNAMAPTMEN1KMT2AALOX5 | |
| SCHEMBL5202463 | 0.78 | TDP1 (0.42) | TDP1TBXA2RLMNAMAPTMEN1 | |
| SCHEMBL5202456 | 0.78 | TDP1 (0.42) | TDP1TBXA2RLMNAMAPTMEN1 | |
| SCHEMBL5201500 | 0.78 | LMNA (0.44) | TDP1TBXA2RLMNAMAPTMEN1 | |
| SCHEMBL5205573 | 0.78 | LMNA (0.44) | TDP1TBXA2RLMNAMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7160887-B1 | Aromatic amine derivatives, their production and use | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2007-01-09 | — | — | US | disclosed |