Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.44 |
| ▸ | MAPT | P10636 | 8/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | MEN1 | O00255 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.37 |
| ▸ | ALPG | P10696 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5205573 | 1.00 | LMNA (0.44) | LMNAMAPTNPSR1ALDH1A1MEN1 | |
| SCHEMBL6177071 | 0.85 | PTGER4 (0.47) | LMNAMAPTNPSR1ALDH1A1MEN1 | |
| SCHEMBL6175825 | 0.85 | PTGER4 (0.47) | LMNAMAPTNPSR1ALDH1A1MEN1 | |
| SCHEMBL6175334 | 0.85 | PTGER4 (0.47) | LMNAMAPTNPSR1ALDH1A1MEN1 | |
| SCHEMBL5206336 | 0.84 | L3MBTL1 (0.41) | LMNAMEN1KMT2APTGER4CYP1A2 | |
| SCHEMBL6180524 | 0.78 | TDP1 (0.47) | LMNAMAPTNPSR1MEN1KMT2A | |
| SCHEMBL6180530 | 0.78 | TDP1 (0.47) | LMNAMAPTNPSR1MEN1KMT2A | |
| SCHEMBL5205566 | 0.78 | TDP1 (0.41) | LMNAMAPTNPSR1ALDH1A1MEN1 | |
| SCHEMBL5201497 | 0.78 | TDP1 (0.41) | LMNAMAPTNPSR1ALDH1A1MEN1 | |
| SCHEMBL5201504 | 0.76 | TDP1 (0.47) | LMNAMAPTNPSR1ALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7160887-B1 | Aromatic amine derivatives, their production and use | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2007-01-09 | — | — | US | disclosed |