Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGDS | O60760 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | TLR7 | Q9NYK1 | 5/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.38 |
| ▸ | CDC25A | P30304 | 1/20 | 0.38 |
| ▸ | CDC25B | P30305 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.36 |
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3065517 | 0.76 | MAPT (0.54) | CYP1A2CYP2C19ALDH1A1POLBNPC1 | |
| SCHEMBL27609155 | 0.76 | ALDH1A1 (0.46) | HPGDSKDM4EALDH1A1TLR7 | |
| SCHEMBL7465829 | 0.76 | ALDH1A1 (0.37) | HPGDSHPGDCYP1A2CYP3A4CYP2C9 | |
| SCHEMBL5200407 | 0.75 | KDM4E (0.41) | HPGDSKDM4EALDH1A1 | |
| SCHEMBL3062139 | 0.74 | HTR2B (0.48) | HPGDSHPGDCYP2C9CYP2C19KDM4E | |
| SCHEMBL722692 | 0.74 | HPGD (0.64) | HPGDSHPGDCYP1A2CYP3A4CYP2C9 | |
| SCHEMBL7460091 | 0.74 | HPGDS (0.38) | HPGDSHPGDKDM4EALDH1A1TLR7 | |
| SCHEMBL3569039 | 0.73 | HDAC1 (0.52) | HPGDSHPGDCYP1A2CYP3A4CYP2C9 | |
| SCHEMBL31216572 | 0.72 | HTR3E (0.37) | HPGDCYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL3818165 | 0.72 | MAPT (0.51) | HPGDSCYP1A2CYP3A4CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1817030-A2 | INDUCIBLE NITRIC OXIDE SYNTHASE DIMERIZATION INHIBITORS | Kalypsys, Inc. (US) | 2007-08-15 | — | — | EP | disclosed |
| WO-2006060424-A2 | INDUCIBLE NITRIC OXIDE SYNTHASE DIMERIZATION INHIBITORS | KALYPSYS, INC. (US) | 2006-06-08 | — | — | WO | disclosed |