Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP2K7 | O14733 | 1/20 | 0.37 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.36 |
| ▸ | MME | P08473 | 1/20 | 0.36 |
| ▸ | P2RX4 | Q99571 | 2/20 | 0.36 |
| ▸ | TAOK1 | Q7L7X3 | 1/20 | 0.36 |
| ▸ | TAOK3 | Q9H2K8 | 1/20 | 0.36 |
| ▸ | PTGIR | P43119 | 1/20 | 0.35 |
| ▸ | CFD | P00746 | 1/20 | 0.35 |
| ▸ | PLAU | P00749 | 1/20 | 0.35 |
| ▸ | RORC | P51449 | 1/20 | 0.34 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.34 |
| ▸ | BACE1 | P56817 | 1/20 | 0.34 |
| ▸ | CSF1R | P07333 | 1/20 | 0.34 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.34 |
| ▸ | KIT | P10721 | 1/20 | 0.34 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.34 |
| ▸ | FLT3 | P36888 | 1/20 | 0.34 |
| ▸ | BRAF | P15056 | 1/20 | 0.34 |
| ▸ | KDR | P35968 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL5202455 | 0.94 | MCHR1 (0.39) | MMEP2RX4PTGIRCFDPLAU | |
| Trifluoroacetic Acid SCHEMBL5205693 | 0.93 | CSF1R (0.39) | MAP2K7EPHX2P2RX4CSF1RPDGFRB | |
| Trifluoroacetic Acid SCHEMBL5204683 | 0.91 | DGAT2 (0.41) | EPHX2MMETAOK1TAOK3PLAU | |
| Trifluoroacetic Acid SCHEMBL5208369 | 0.90 | BACE1 (0.45) | EPHX2MMETAOK1TAOK3PLAU | |
| Trifluoroacetic Acid SCHEMBL5205650 | 0.90 | TAOK1 (0.38) | MAP2K7EPHX2P2RX4TAOK1TAOK3 | |
| Trifluoroacetic Acid SCHEMBL5205396 | 0.89 | TSPO (0.41) | EPHX2TAOK1TAOK3MEN1KMT2A | |
| Trifluoroacetic Acid SCHEMBL5202498 | 0.89 | EPHX2 (0.38) | MAP2K7EPHX2P2RX4 | |
| Trifluoroacetic Acid SCHEMBL5208081 | 0.88 | EPHX2 (0.37) | EPHX2TAOK1TAOK3PLAUBACE1 | |
| Trifluoroacetic Acid SCHEMBL5208213 | 0.88 | TAOK1 (0.37) | EPHX2TAOK1TAOK3PLAU | |
| Trifluoroacetic Acid SCHEMBL5202054 | 0.88 | TSPO (0.39) | EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7160887-B1 | Aromatic amine derivatives, their production and use | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2007-01-09 | — | — | US | disclosed |
| EP-1123918-B1 | AROMATIC AMINE DERIVATIVES, PROCESS FOR THE PREPARATION THEREOF AND AGENTS CONTAINING THE SAME | TAKEDA PHARMACEUTICAL (JP) | 2005-03-09 | — | — | EP | disclosed |