Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 5/20 | 0.37 |
| ▸ | HTR5A | P47898 | 1/20 | 0.36 |
| ▸ | BACE1 | P56817 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | TAOK1 | Q7L7X3 | 1/20 | 0.35 |
| ▸ | TAOK3 | Q9H2K8 | 1/20 | 0.35 |
| ▸ | PLAU | P00749 | 1/20 | 0.34 |
| ▸ | SSTR5 | P35346 | 1/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.33 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.33 |
| ▸ | TPSAB1 | Q15661 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL5201717 | 0.94 | SSTR5 (0.39) | HTR5ABACE1KDM4EALDH1A1HTT | |
| Trifluoroacetic Acid SCHEMBL5208369 | 0.91 | BACE1 (0.45) | EPHX2BACE1TAOK1TAOK3PLAU | |
| Trifluoroacetic Acid SCHEMBL5205650 | 0.91 | TAOK1 (0.38) | EPHX2BACE1KDM4EALDH1A1HTT | |
| Trifluoroacetic Acid SCHEMBL5204683 | 0.91 | DGAT2 (0.41) | EPHX2HTR5AKDM4EALDH1A1HTT | |
| Trifluoroacetic Acid SCHEMBL5202498 | 0.90 | EPHX2 (0.38) | EPHX2KDM4EALDH1A1HTTTDP1 | |
| Trifluoroacetic Acid SCHEMBL5205396 | 0.89 | TSPO (0.41) | EPHX2HTR5AKDM4EALDH1A1HTT | |
| Trifluoroacetic Acid SCHEMBL5202054 | 0.89 | TSPO (0.39) | EPHX2TPSAB1 | |
| Trifluoroacetic Acid SCHEMBL5201658 | 0.88 | MAP2K7 (0.37) | EPHX2BACE1TAOK1TAOK3PLAU | |
| Trifluoroacetic Acid SCHEMBL5208213 | 0.88 | TAOK1 (0.37) | EPHX2HTR5AKDM4EALDH1A1HTT | |
| Trifluoroacetic Acid SCHEMBL5203101 | 0.87 | TDP1 (0.36) | EPHX2TDP1TAOK1TAOK3TPSAB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7160887-B1 | Aromatic amine derivatives, their production and use | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2007-01-09 | — | — | US | disclosed |
| EP-1123918-B1 | AROMATIC AMINE DERIVATIVES, PROCESS FOR THE PREPARATION THEREOF AND AGENTS CONTAINING THE SAME | TAKEDA PHARMACEUTICAL (JP) | 2005-03-09 | — | — | EP | disclosed |
| EP-1123918-A1 | AROMATIC AMINE DERIVATIVES, PROCESS FOR THE PREPARATION THEREOF AND AGENTS CONTAINING THE SAME | Takeda Chemical Industries, Ltd. (JP) | 2001-08-16 | — | — | EP | disclosed |