Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | ABAT | P80404 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | TEAD4 | Q15561 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4124188 | 0.77 | ALDH1A1 (0.50) | TDP1ABATGAAALDH1A1HSD17B10 | |
| SCHEMBL2705958 | 0.77 | ALDH1A1 (0.50) | TDP1ABATGAAALDH1A1HSD17B10 | |
| SCHEMBL5861572 | 0.77 | ALDH1A1 (0.50) | TDP1ABATGAAALDH1A1HSD17B10 | |
| SCHEMBL24700263 | 0.76 | TDP1 (0.54) | TDP1GAAALDH1A1HSD17B10LMNA | |
| SCHEMBL6047683 | 0.75 | MME (0.51) | TDP1ABATGAAALDH1A1HSD17B10 | |
| SCHEMBL990038 | 0.75 | TDP1 (0.70) | TDP1GAAALDH1A1HSD17B10LMNA | |
| SCHEMBL9080692 | 0.74 | TDP1 (0.42) | TDP1ABATALDH1A1HSD17B10LMNA | |
| SCHEMBL9080695 | 0.74 | TDP1 (0.42) | TDP1ABATALDH1A1HSD17B10LMNA | |
| SCHEMBL524374 | 0.73 | APAF1 (0.62) | ALDH1A1HSD17B10LMNACYP3A4ALOX15 | |
| SCHEMBL653596 | 0.73 | APAF1 (0.62) | ALDH1A1HSD17B10LMNACYP3A4ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1805197-A1 | HEMATOLOGICAL CANCER PROFILING SYSTEM | Med Biogene Inc (CA) | 2007-07-11 | — | — | EP | disclosed |
| WO-2006034573-A1 | HEMATOLOGICAL CANCER PROFILING SYSTEM | MED BIOGENE INC. (CA) | 2006-04-06 | — | — | WO | disclosed |