Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 1/20 | 0.39 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.36 |
| ▸ | SIRT5 | Q9NXA8 | 3/20 | 0.36 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.34 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.34 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.34 |
| ▸ | CDC25A | P30304 | 1/20 | 0.34 |
| ▸ | CDC25B | P30305 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5202191 | 0.80 | PPARG (0.42) | FFAR1PTGDR2PPARGALDH1A1 | |
| SCHEMBL5208051 | 0.77 | MEN1 (0.41) | KMT2AMEN1LMNAPTGER4ALDH1A1 | |
| SCHEMBL5202385 | 0.77 | MEN1 (0.41) | KMT2AMEN1LMNAPTGER4ALDH1A1 | |
| SCHEMBL5206639 | 0.76 | KDM4E (0.36) | KMT2AMEN1 | |
| SCHEMBL5205373 | 0.74 | TSPO (0.40) | P2RX4FFAR1 | |
| SCHEMBL5208118 | 0.73 | FDFT1 (0.39) | P2RY1KMT2AMEN1FFAR1NPSR1 | |
| SCHEMBL5206633 | 0.72 | KDM4E (0.40) | KMT2AMEN1ALDH1A1NPSR1 | |
| SCHEMBL5205312 | 0.72 | PPARG (0.40) | PPARGALDH1A1 | |
| SCHEMBL5205112 | 0.71 | MEN1 (0.37) | P2RX4KMT2AMEN1LMNAPTGER4 | |
| SCHEMBL27637321 | 0.70 | L3MBTL1 (0.50) | L3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7160887-B1 | Aromatic amine derivatives, their production and use | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2007-01-09 | — | — | US | disclosed |
| EP-1123918-B1 | AROMATIC AMINE DERIVATIVES, PROCESS FOR THE PREPARATION THEREOF AND AGENTS CONTAINING THE SAME | TAKEDA PHARMACEUTICAL (JP) | 2005-03-09 | — | — | EP | disclosed |
| EP-1123918-A1 | AROMATIC AMINE DERIVATIVES, PROCESS FOR THE PREPARATION THEREOF AND AGENTS CONTAINING THE SAME | Takeda Chemical Industries, Ltd. (JP) | 2001-08-16 | — | — | EP | disclosed |