Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSPO | P30536 | 1/20 | 0.40 |
| ▸ | FDFT1 | P37268 | 5/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.32 |
| ▸ | CNR1 | P21554 | 2/20 | 0.31 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5208118 | 0.92 | FDFT1 (0.39) | TSPOFDFT1FFAR1MDM2 | |
| SCHEMBL5205377 | 0.82 | PPARG (0.40) | TSPOFDFT1 | |
| SCHEMBL5203510 | 0.76 | PPARG (0.39) | TSPOFDFT1MDM2 | |
| SCHEMBL5205254 | 0.75 | TSPO (0.38) | TSPOFDFT1 | |
| SCHEMBL5202185 | 0.74 | NR4A2 (0.39) | FFAR1P2RX4 | |
| SCHEMBL5204994 | 0.71 | ALDH1A1 (0.40) | TSPOP2RX4 | |
| SCHEMBL5204545 | 0.67 | KMT2A (0.41) | — | |
| Hydrochloric Acid SCHEMBL5201776 | 0.67 | AHCY (0.39) | TSPOCNR1P2RX4 | |
| SCHEMBL5208000 | 0.66 | HDAC1 (0.44) | TSPOFFAR1 | |
| SCHEMBL27559984 | 0.66 | SLC7A5 (0.43) | FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7160887-B1 | Aromatic amine derivatives, their production and use | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2007-01-09 | — | — | US | disclosed |
| EP-1123918-B1 | AROMATIC AMINE DERIVATIVES, PROCESS FOR THE PREPARATION THEREOF AND AGENTS CONTAINING THE SAME | TAKEDA PHARMACEUTICAL (JP) | 2005-03-09 | — | — | EP | disclosed |
| EP-1123918-A1 | AROMATIC AMINE DERIVATIVES, PROCESS FOR THE PREPARATION THEREOF AND AGENTS CONTAINING THE SAME | Takeda Chemical Industries, Ltd. (JP) | 2001-08-16 | — | — | EP | disclosed |