Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.74 |
| ▸ | MAPT | P10636 | 9/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.66 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.64 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.64 |
| ▸ | RECQL | P46063 | 1/20 | 0.63 |
| ▸ | POLB | P06746 | 2/20 | 0.62 |
| ▸ | HTR6 | P50406 | 2/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1920553 | 0.94 | HPGD (0.73) | HPGDMAPTALDH1A1SMN1; SMN2MAPK1 | |
| Hydrochloric Acid SCHEMBL22634512 | 0.93 | HPGD (0.71) | HPGDMAPTALDH1A1SMN1; SMN2MAPK1 | |
| SCHEMBL5237456 | 0.89 | MAPT (0.62) | HPGDMAPTALDH1A1SMN1; SMN2MAPK1 | |
| SCHEMBL6653754 | 0.87 | HPGD (0.97) | HPGDMAPTALDH1A1SMN1; SMN2MAPK1 | |
| SCHEMBL7050664 | 0.86 | HPGD (0.88) | HPGDMAPTALDH1A1SMN1; SMN2MAPK1 | |
| SCHEMBL3837554 | 0.86 | HPGD (1.00) | HPGDMAPTALDH1A1SMN1; SMN2MAPK1 | |
| SCHEMBL573146 | 0.86 | HPGD (1.00) | HPGDMAPTALDH1A1SMN1; SMN2MAPK1 | |
| SCHEMBL2202741 | 0.83 | ALDH1A1 (0.78) | HPGDMAPTALDH1A1SMN1; SMN2MAPK1 | |
| SCHEMBL2921548 | 0.83 | MAPT (0.65) | HPGDMAPTALDH1A1SMN1; SMN2MAPK1 | |
| Tert-Butyl Formate SCHEMBL27839256 | 0.83 | HPGD (0.57) | HPGDMAPTALDH1A1SMN1; SMN2MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1417184-B1 | COMPOSITION FOR DYEING KERATINOUS FIBRES CONTAINING A PARAPHENYLENEDIAMINE SUBSTITUTED BY A DIAZACYCLOHEPTANE RADICAL | OREAL (FR) | 2007-08-29 | — | — | EP | disclosed |
| US-7241317-B2 | Composition for dyeing keratin fibers comprising at least one para-phenylenediamine substituted with a diazacycloheptane radical | L'OREAL, S.A. (FR) | 2007-07-10 | — | — | US | disclosed |
| US-7241317-B2 | Composition for dyeing keratin fibers comprising at least one para-phenylenediamine substituted with a diazacycloheptane radical | L'OREAL, S.A. (FR) | 2007-07-10 | — | — | US | disclosed |
| US-7241317-B2 | Composition for dyeing keratin fibers comprising at least one para-phenylenediamine substituted with a diazacycloheptane radical | L'OREAL, S.A. (FR) | 2007-07-10 | — | — | US | disclosed |
| US-20050102769-A1 | Composition for dyeing keratinous fibers containing a paraphenylenediamine substituted by a diazacycloheptane radical | L'OREAL S.A. (FR) | 2005-05-19 | — | — | US | disclosed |
| EP-1417184-A1 | COMPOSITION FOR DYEING KERATINOUS FIBRES CONTAINING A PARAPHENYLENEDIAMINE SUBSTITUTED BY A DIAZACYCLOHEPTANE RADICAL | L'OREAL (FR) | 2004-05-12 | — | — | EP | disclosed |
| WO-2003014093-A1 | COMPOSITION FOR DYEING KERATINOUS FIBRES CONTAINING A PARAPHENYLENEDIAMINE SUBSTITUTED BY A DIAZACYCLOHEPTANE RADICAL | L'OREAL (FR) | 2003-02-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050102769-A1 | Composition for dyeing keratinous fibers containing a paraphenylenediamine substituted by a diazacycloheptane radical | KRT18, HPD, PPOX | HPGD 20/4885MAPT 2115/4885ALDH1A1 314/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.