Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 10/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.61 |
| ▸ | RECQL | P46063 | 1/20 | 0.59 |
| ▸ | POLB | P06746 | 3/20 | 0.59 |
| ▸ | HPGD | P15428 | 2/20 | 0.58 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.55 |
| ▸ | HTR6 | P50406 | 2/20 | 0.54 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.52 |
| ▸ | HTT | P42858 | 2/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2921548 | 0.94 | MAPT (0.65) | MAPTALDH1A1SMN1; SMN2MAPK1RECQL | |
| SCHEMBL5202277 | 0.89 | HPGD (0.74) | MAPTALDH1A1SMN1; SMN2MAPK1RECQL | |
| SCHEMBL27518071 | 0.87 | HPGD (0.74) | MAPTALDH1A1SMN1; SMN2MAPK1HPGD | |
| SCHEMBL1920553 | 0.83 | HPGD (0.73) | MAPTALDH1A1SMN1; SMN2MAPK1RECQL | |
| Hydrochloric Acid SCHEMBL22634512 | 0.82 | HPGD (0.71) | MAPTALDH1A1SMN1; SMN2MAPK1RECQL | |
| SCHEMBL30307826 | 0.81 | MAPT (0.75) | MAPTALDH1A1SMN1; SMN2MAPK1RECQL | |
| SCHEMBL28954967 | 0.81 | MAPT (0.75) | MAPTALDH1A1SMN1; SMN2MAPK1RECQL | |
| SCHEMBL2202741 | 0.81 | ALDH1A1 (0.78) | MAPTALDH1A1SMN1; SMN2MAPK1RECQL | |
| SCHEMBL5231120 | 0.79 | ADRB1 (0.86) | ADRB1 | |
| SCHEMBL30900326 | 0.79 | SIRT6 (0.67) | MAPTALDH1A1MAPK1HPGDHTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070219234-A1 | Thienopyridine Derivatives | SANKYO COMPANY, LIMITED (JP) | 2007-09-20 | — | — | US | disclosed |
| EP-1764367-A1 | THIENOPYRIDINE DERIVATIVES | Sankyo Company, Limited (JP) | 2007-03-21 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070219234-A1 | Thienopyridine Derivatives | RASGRP1, NRAS, HRH3 | MAPT 4452/4885ALDH1A1 1073/4885SMN1; SMN2 1957/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.