Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 13/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.50 |
| ▸ | NPC1 | O15118 | 10/20 | 0.49 |
| ▸ | XDH | P47989 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | XBP1 | P17861 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5273697 | 0.83 | RAB9A (0.49) | RAB9AALDH1A1NPC1SMN1; SMN2MAPT | |
| SCHEMBL2119714 | 0.83 | RAB9A (0.54) | RAB9AALDH1A1NPC1SMN1; SMN2KMT2A | |
| SCHEMBL5274776 | 0.83 | MAPK14 (0.53) | RAB9AALDH1A1NPC1XDHSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL5405647 | 0.81 | MAPK14 (0.52) | RAB9AALDH1A1NPC1XDHSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL5414203 | 0.81 | NPBWR1 (0.44) | ALDH1A1SMN1; SMN2NPSR1LMNAPKM | |
| Hydrochloric Acid SCHEMBL11094598 | 0.81 | RAB9A (0.53) | RAB9AALDH1A1NPC1SMN1; SMN2KMT2A | |
| SCHEMBL3251404 | 0.77 | RAB9A (0.56) | RAB9AALDH1A1NPC1XDHSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL5413922 | 0.75 | RAB9A (0.54) | RAB9AALDH1A1NPC1XDHSMN1; SMN2 | |
| SCHEMBL10767724 | 0.72 | RAB9A (0.50) | RAB9AALDH1A1NPC1XDHSMN1; SMN2 | |
| SCHEMBL1692019 | 0.72 | RIPK2 (0.71) | RAB9AALDH1A1NPC1SMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1408025-B1 | 3,3-DIALKOXY-2-HYDROXYIMINOPROPIONITRILES, PROCESS FOR PREPARATION THEREOF AND PROCESS OF PREPARING 5-AMINO -4-NITROSOPYRAZOLES OR SALTS THEREOF BY THE USE OF THE SAME | UBE INDUSTRIES (JP) | 2007-11-21 | — | — | EP | disclosed |
| EP-1817379-A2 | PYRAZOLE AZOMETHINES AND COLORANTS CONTAINING THESE COMPOUNDS | The Procter and Gamble Company (US) | 2007-08-15 | — | — | EP | disclosed |
| US-7256304-B2 | Process for producing 3-unsubstituted 5-amino-4-nitrosopyrazole compound, and 2-hydroxyimino-3-oxopropionitrile, 3-hydrazono-2-hydroxyiminopropionitrile compound, and processes for producing these | UBE INDUSTRIES, LTD. (JP) | 2007-08-14 | — | — | US | disclosed |
| US-7227032-B2 | 3,3-dialkoxy-2-hydroxyiminopropionitriles, process for preparation thereof and process of preparing 5-amino-4-nitrosopyrazoles or salts thereof by the use of the same | UBE INDUSTRIES, LTD. (JP) | 2007-06-05 | — | — | US | disclosed |
| US-20070033742-A1 | Pyrazole azomethines and colorants containing these compounds | PROCTER & GAMBLE COMPANY, THE | 2007-02-15 | — | — | US | disclosed |
| WO-2006060564-A2 | PYRAZOLE AZOMETHINES AND COLORANTS CONTAINING THESE COMPOUNDS | THE PROCTER & GAMBLE COMPANY (US) | 2006-06-08 | — | — | WO | disclosed |
| US-20050096472-A1 | Process for producing 3-unsubstituted 5-amino-4-nitrosopyrazole compound, and 2-hydroxyimino-3-oxopropionitrile, 3-hydrazono-2-hydroxyiminopropionitrile compound, and processes for producing these | UBE INDUSTRIES, LTD. (JP) | 2005-05-05 | — | — | US | disclosed |
| EP-1475369-A1 | PROCESS FOR PRODUCING 3-UNSUBSTITUTED 5-AMINO-4-NITROSOPYRAZOLE COMPOUND, AND 2-HYDROXYIMINO-3-OXOPROPIONITRILE, 3-HYDRAZONO-2-HYDROXYIMINOPROPIONITRILE COMPOUND, AND PROCESSES FOR PRODUCING THESE | Ube Industries, Ltd. (JP) | 2004-11-10 | — | — | EP | disclosed |
| US-20040116732-A1 | 3,3-Dialkoxy-2-hydroxyiminopropionitriles, process for preparation thereof and process of preparing 5-amino-4-nitrosopyrazoles or salts thereof by the use of the same | UBE INDUSTRIES, LTD. (JP) | 2004-06-17 | — | — | US | disclosed |
| EP-1408025-A1 | 3,3-DIALKOXY-2-HYDROXYIMINOPROPIONITRILES, PROCESS FOR PREPARATION THEREOF AND PROCESS OF PREPARING 5-AMINO -4-NITROSOPYRAZOLES OR SALTS THEREOF BY THE USE OF THE SAME | Ube Industries, Ltd. (JP) | 2004-04-14 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070033742-A1 | Pyrazole azomethines and colorants containing these compounds | KRT18, NOX5, TUBB3 | RAB9A 3691/4885ALDH1A1 193/4885NPC1 4751/4885 |
| US-20050096472-A1 | Process for producing 3-unsubstituted 5-amino-4-nitrosopyrazole compound, and 2-hydroxyimino-3-oxopropionitrile, 3-hydrazono-2-hydroxyiminopropionitrile compound, and processes for producing these | CYP1A1, CYP2E1, NOS3 | RAB9A 3553/4885ALDH1A1 182/4885NPC1 3817/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.