Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTOR | P42345 | 1/20 | 0.33 |
| ▸ | NFE2L2 | Q16236 | 4/20 | 0.33 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.31 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.31 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.31 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | GLA | P06280 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13082489 | 0.81 | ALDH1A1 (0.40) | ALDH1A1TDP1KDM4ETP53GLA | |
| SCHEMBL11615247 | 0.75 | CYP2A6 (0.32) | MTOR | |
| SCHEMBL4383170 | 0.74 | DHODH (0.35) | SORT1SLC22A12CYP1A2CYP3A4ALDH1A1 | |
| SCHEMBL30547062 | 0.74 | DHODH (0.35) | SORT1SLC22A12CYP1A2CYP3A4ALDH1A1 | |
| SCHEMBL15147449 | 0.72 | CYP1A2 (0.37) | SORT1HRH4SLC22A12CYP1A2CYP3A4 | |
| SCHEMBL5202743 | 0.72 | SORT1 (0.35) | NFE2L2SORT1SLC22A12CYP1A2CYP3A4 | |
| SCHEMBL20288393 | 0.72 | TLR9 (0.34) | SORT1HRH4AAK1CYP1A2CYP3A4 | |
| SCHEMBL21092870 | 0.71 | S1PR1 (0.33) | SORT1HRH4CYP1A2CYP3A4ALDH1A1 | |
| SCHEMBL22056622 | 0.71 | P2RX7 (0.38) | CYP1A2CYP3A4ALDH1A1ALOX15TSHR | |
| SCHEMBL4383164 | 0.71 | SORT1 (0.33) | SORT1CYP1A2CYP3A4ALDH1A1ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014023531-A1 | TRIFLUOROMETHYLPYRIDINE CARBOXAMIDES AS PESTICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2014-02-13 | — | — | WO | disclosed |
| EP-1654253-B1 | SUBSTITUTED 3-PYRROLIDIN-INDOLE DERIVATIVES | GRUENENTHAL GMBH (DE) | 2007-01-03 | — | — | EP | disclosed |