SCHEMBL5202849

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL939974	0.84	POLB (0.44)	KDM4EKMT2AMEN1CYP3A4GAA
	SCHEMBL17469085	0.84	PKM (0.39)	MAPTKDM4ESMN1; SMN2KMT2AMEN1
	SCHEMBL28783815	0.82	LMNA (0.39)	MAPTKDM4EKMT2AMEN1CYP3A4
	SCHEMBL3060859	0.82	MEN1 (0.39)	MAPTKDM4ESMN1; SMN2KMT2AMEN1
	Benzamide SCHEMBL27827170	0.81	TSHR (0.43)	MAPTKDM4ESMN1; SMN2CYP3A4BLM
	SCHEMBL354031	0.79	GAA (0.43)	MAPTKDM4ESMN1; SMN2KMT2AMEN1
	SCHEMBL11545754	0.78	TSHR (0.35)	MAPTKDM4ESMN1; SMN2KMT2ACYP3A4
	SCHEMBL11545682	0.77	TSHR (0.36)	MAPTKDM4ESMN1; SMN2CYP3A4BLM
	SCHEMBL11547934	0.76	LMNA (0.34)	MAPTKDM4ESMN1; SMN2KMT2ACYP3A4
	SCHEMBL8384735	0.76	PKM (0.39)	MAPTKDM4EKMT2AMEN1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.