Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 4/20 | 0.33 |
| ▸ | CA1 | P00915 | 2/20 | 0.33 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | CA9 | Q16790 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | BLM | P54132 | 1/20 | 0.30 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | CA12 | O43570 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11545754 | 0.80 | TSHR (0.35) | TSHRMAPTLMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL5202849 | 0.77 | MAPT (0.41) | MAPTLMNAPOLBALDH1A1SMN1; SMN2 | |
| SCHEMBL11544982 | 0.74 | TSHR (0.40) | TSHRCA2 | |
| SCHEMBL11546972 | 0.74 | GLA (0.38) | TSHRMAPTLMNAPOLBALDH1A1 | |
| SCHEMBL11545003 | 0.73 | TSHR (0.40) | TSHRMAPTALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL11544871 | 0.72 | PARP1 (0.39) | TSHRMAPTPOLBALDH1A1SMN1; SMN2 | |
| SCHEMBL11546538 | 0.72 | LMNA (0.33) | MAPTCA1CA2CA9LMNA | |
| SCHEMBL11480103 | 0.71 | CA1 (0.34) | MAPTCA1CA2CA9LMNA | |
| SCHEMBL11549665 | 0.70 | MEN1 (0.43) | TSHRMAPTCA1CA2CA9 | |
| SCHEMBL11545798 | 0.69 | SIRT2 (0.38) | ALDH1A1CYP3A4KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4145363-A | ANTIASTHMATICS | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1979-03-20 | — | — | US | disclosed |
| US-4063025-A | PROPHYLAXIS, ANTIASTHMATIC | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JA) | 1977-12-13 | — | — | US | disclosed |