Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.31 |
| ▸ | JAK2 | O60674 | 1/20 | 0.31 |
| ▸ | JAK3 | P52333 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11545682 | 0.80 | TSHR (0.36) | TSHRLMNAGLAMAPTSMN1; SMN2 | |
| SCHEMBL11546972 | 0.78 | GLA (0.38) | TSHRLMNAGLAMAPTCYP3A4 | |
| SCHEMBL5202849 | 0.78 | MAPT (0.41) | LMNAGLAMAPTSMN1; SMN2CYP3A4 | |
| SCHEMBL11544982 | 0.75 | TSHR (0.40) | TSHRKMT2A | |
| SCHEMBL11545003 | 0.74 | TSHR (0.40) | TSHRMAPTSMN1; SMN2KDM4EKMT2A | |
| SCHEMBL11544871 | 0.73 | PARP1 (0.39) | TSHRMAPTSMN1; SMN2CYP3A4KDM4E | |
| SCHEMBL11547934 | 0.71 | LMNA (0.34) | LMNAMAPTSMN1; SMN2CYP3A4BLM | |
| SCHEMBL11549665 | 0.71 | MEN1 (0.43) | TSHRLMNAMAPTSMN1; SMN2KDM4E | |
| SCHEMBL11545798 | 0.70 | SIRT2 (0.38) | CYP3A4JAK2JAK3KDM4EKMT2A | |
| SCHEMBL11474476 | 0.70 | ATM (0.35) | LMNAMAPTSMN1; SMN2CYP3A4BLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4166820-A | Selenium compounds | SPALLHOLZ JULIAN E | 1979-09-04 | — | — | US | disclosed |