Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | CRHR1 | P34998 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.31 |
| ▸ | ORAI1 | Q96D31 | 1/20 | 0.31 |
| ▸ | ORAI2 | Q96SN7 | 1/20 | 0.31 |
| ▸ | ORAI3 | Q9BRQ5 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5207796 | 0.78 | CYP3A4 (0.52) | MEN1CYP3A4KMT2ACA9CYP1A2 | |
| SCHEMBL6628469 | 0.78 | RXFP1 (0.39) | MEN1CYP3A4KMT2ACA12CA1 | |
| SCHEMBL28905844 | 0.77 | BRD9 (0.46) | MEN1KMT2ALMNAALDH1A1MAPT | |
| SCHEMBL6341004 | 0.76 | ENPP2 (0.39) | CYP3A4CYP2C19CA1CA2ALDH1A1 | |
| SCHEMBL5206042 | 0.76 | CA12 (0.35) | CYP3A4CA12CA1CA2CA7 | |
| SCHEMBL5206460 | 0.76 | CA12 (0.35) | MEN1CYP3A4KMT2ACA12CA1 | |
| SCHEMBL5208181 | 0.74 | CNKSR1 (0.35) | MEN1CYP3A4KMT2ACA12CA1 | |
| SCHEMBL5203894 | 0.73 | CYP3A4 (0.38) | MEN1CYP3A4KMT2AALDH1A1USP2 | |
| SCHEMBL5235564 | 0.73 | ERN1 (0.41) | CRHR1ALDH1A1MAPTL3MBTL1ERN1 | |
| SCHEMBL2178296 | 0.72 | CA2 (0.61) | CYP3A4CYP2C19CA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1403251-B1 | BIS(2-ARYL-5-PYRIDYL) DERIVATIVE | KOWA CO (JP) | 2007-07-18 | — | — | EP | disclosed |
| EP-1403251-A1 | BIS(2-ARYL-5-PYRIDYL) DERIVATIVE | Kowa Co., Ltd. (JP) | 2004-03-31 | — | — | EP | disclosed |