Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | BRD4 | O60885 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.31 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.31 |
| ▸ | SYK | P43405 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6339576 | 0.84 | GAA (0.34) | MAPK1FKBP1AGAALMNAMAPT | |
| SCHEMBL5203576 | 0.80 | TNFRSF1A (0.45) | MAPK1LMNAMAPTL3MBTL1ALDH1A1 | |
| SCHEMBL5203599 | 0.79 | MAPK1 (0.36) | MAPK1FKBP1AGAASMN1; SMN2SLC6A5 | |
| SCHEMBL19438931 | 0.77 | L3MBTL1 (0.47) | FKBP1AGAALMNAMAPTL3MBTL1 | |
| SCHEMBL5208220 | 0.77 | SMN1; SMN2 (0.48) | MAPK1GAAMAPTL3MBTL1ALDH1A1 | |
| SCHEMBL20915927 | 0.76 | TSHR (0.48) | FKBP1AGAAMAPTL3MBTL1ALDH1A1 | |
| SCHEMBL5205549 | 0.74 | HTR2A (0.49) | LMNAMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL20605146 | 0.72 | SMN1; SMN2 (0.50) | MAPK1FKBP1AGAALMNAMAPT | |
| SCHEMBL5203497 | 0.72 | CYP2C9 (0.35) | MAPK1MAPTL3MBTL1ALDH1A1MEN1 | |
| SCHEMBL5207796 | 0.71 | CYP3A4 (0.52) | MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1403251-B1 | BIS(2-ARYL-5-PYRIDYL) DERIVATIVE | KOWA CO (JP) | 2007-07-18 | — | — | EP | disclosed |
| EP-1403251-A1 | BIS(2-ARYL-5-PYRIDYL) DERIVATIVE | Kowa Co., Ltd. (JP) | 2004-03-31 | — | — | EP | disclosed |