Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 8/20 | 0.48 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.48 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.44 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.40 |
| ▸ | PLK1 | P53350 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Dimethylamine SCHEMBL5205078 | 0.96 | PTGS2 (0.45) | PTGS2PTGS1PDPK1CHRNA7PLK1 | |
| SCHEMBL5207409 | 0.89 | PTGS2 (0.49) | PTGS2PTGS1PDPK1CHRNA7 | |
| SCHEMBL5865304 | 0.89 | PTGS1 (0.46) | PTGS2PTGS1PDPK1CHRNA7 | |
| SCHEMBL5205172 | 0.89 | PTGS2 (0.49) | PTGS2PTGS1CHRNA7 | |
| SCHEMBL5207661 | 0.89 | KIF11 (0.49) | PTGS2PTGS1PDPK1CHRNA7 | |
| SCHEMBL5865490 | 0.89 | PTGS2 (0.46) | PTGS2PTGS1CHRNA7 | |
| SCHEMBL5205063 | 0.89 | PTGS2 (0.53) | PTGS2PTGS1PDPK1CHRNA7 | |
| SCHEMBL5865465 | 0.89 | PTGS2 (0.53) | PTGS2PTGS1 | |
| SCHEMBL5207586 | 0.88 | PTGS2 (0.47) | PTGS2PTGS1CHRNA7 | |
| SCHEMBL5239915 | 0.88 | PTGS2 (0.50) | PTGS2PTGS1PDPK1CHRNA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1688554-A | 1,2, 4-triazole derivatives, process for preparing the same and pharmaceutical composition containing the same | CJ CORP (KR) | 2005-10-26 | — | — | CN | claimed |
| EP-1273580-B1 | Sulfonyl heteroaryl triazoles as anti-inflammatory and analgesic agents | PFIZER PROD INC (US) | 2005-06-15 | — | — | EP | claimed |
| US-6875779-B2 | Sulfonyl heteroaryl triazoles as anti-inflammatory/analgesic agents | PFIZER INC. (US) | 2005-04-05 | — | — | US | claimed |
| US-20040198735-A1 | Sulfonyl heteroaryl triazoles as anti-inflammatory/analgesic agents | SAKYA SUBAS M (US) | 2004-10-07 | — | — | US | claimed |
| US-20030119835-A1 | Sulfonyl heteroaryl triazoles as anti-inflammatory/analgesic agents | PFIZER PRODUCTS, INC. | 2003-06-26 | — | — | US | claimed |
| EP-1273580-A1 | Sulfonyl heteroaryl triazoles as anti-inflammatory and analgesic agents | Pfizer Products Inc. (US) | 2003-01-08 | — | — | EP | claimed |
| CN-101012203-B | 1,2,4-triazol derivatives, method for preparing the same | CJ CORP | 2011-02-16 | — | — | CN | disclosed |
| CN-100357277-C | 1,2, 4-triazole derivatives, process for preparing the same and pharmaceutical composition containing the same | CJ CORP (KR) | 2007-12-26 | — | — | CN | disclosed |
| CN-101012203-A | 1,2,4-triazol derivatives, method for preparing the same | CJ CORP (KR) | 2007-08-08 | — | — | CN | disclosed |
| EP-1539718-A4 | 1,2,4-TRIAZOLE DERIVATIVE, METHOD FOR PREPARING THE SAME, AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | CJ CORP (KR) | 2007-08-01 | — | — | EP | disclosed |
| US-7019144-B2 | 1,2,4-Triazole derivative, method for preparing the same, and pharmaceutical composition containing the same | CJ CORP. (KR) | 2006-03-28 | — | — | US | disclosed |
| CN-1688554-A | 1,2, 4-triazole derivatives, process for preparing the same and pharmaceutical composition containing the same | CJ CORP (KR) | 2005-10-26 | — | — | CN | disclosed |
| EP-1539718-A1 | 1,2,4-TRIAZOLE DERIVATIVE, METHOD FOR PREPARING THE SAME, AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | CJ Corporation (KR) | 2005-06-15 | — | — | EP | disclosed |
| US-6875779-B2 | Sulfonyl heteroaryl triazoles as anti-inflammatory/analgesic agents | PFIZER INC. (US) | 2005-04-05 | — | — | US | disclosed |
| US-20040198735-A1 | Sulfonyl heteroaryl triazoles as anti-inflammatory/analgesic agents | SAKYA SUBAS M (US) | 2004-10-07 | — | — | US | disclosed |
| US-6753332-B2 | CYCLOOXYGENASE INHIBITORS | PFIZER, INC. | 2004-06-22 | — | — | US | disclosed |
| WO-2004014878-A1 | 1,2,4-TRIAZOLE DERIVATIVE, METHOD FOR PREPARING THE SAME, AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | CJ CORPORATION (KR) | 2004-02-19 | — | — | WO | disclosed |
| US-20030119835-A1 | Sulfonyl heteroaryl triazoles as anti-inflammatory/analgesic agents | PFIZER PRODUCTS, INC. | 2003-06-26 | — | — | US | disclosed |
| JP-2003040887-A | SULFONYL HETEROARYLTRIAZOLE AS ANTIINFLAMMATORY/ ANALGESIC AGENT | PFIZER PROD INC | 2003-02-13 | — | — | JP | disclosed |
| EP-1273580-A1 | Sulfonyl heteroaryl triazoles as anti-inflammatory and analgesic agents | Pfizer Products Inc. (US) | 2003-01-08 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040198735-A1 | Sulfonyl heteroaryl triazoles as anti-inflammatory/analgesic agents | SULT2A1, SULT1A1, SULT1E1 | PTGS2 201/4885PTGS1 51/4885PDPK1 3285/4885 |
| US-20030119835-A1 | Sulfonyl heteroaryl triazoles as anti-inflammatory/analgesic agents | SULT2A1, SULT1A1, SULT1E1 | PTGS2 201/4885PTGS1 51/4885PDPK1 3285/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.