Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1B | Q00975 | 8/20 | 0.52 |
| ▸ | ADAMTS5 | Q9UNA0 | 3/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6174370 | 0.83 | CACNA1B (0.48) | CACNA1BADAMTS5ALDH1A1GAAL3MBTL1 | |
| SCHEMBL5205589 | 0.80 | CACNA1B (0.50) | CACNA1BNPC1RAB9AALDH1A1LMNA | |
| SCHEMBL7834277 | 0.79 | FFAR1 (0.44) | ADAMTS5RAB9AALDH1A1GAAL3MBTL1 | |
| SCHEMBL1730117 | 0.78 | LMNA (0.68) | NPC1RAB9AALDH1A1GAAHTT | |
| SCHEMBL5206113 | 0.78 | ADAMTS5 (0.48) | ADAMTS5NPC1RAB9AALDH1A1GAA | |
| SCHEMBL7242067 | 0.77 | FFAR1 (0.54) | ADAMTS5ALDH1A1HPGDLMNAMEN1 | |
| SCHEMBL1728537 | 0.77 | MAPK14 (0.68) | ALDH1A1GAAL3MBTL1HPGDHTT | |
| SCHEMBL11215406 | 0.77 | CACNA1B (0.63) | CACNA1BGAAL3MBTL1HPGD | |
| SCHEMBL6178139 | 0.77 | CYP1A2 (0.51) | NPC1ALDH1A1GAAL3MBTL1HPGD | |
| SCHEMBL11216479 | 0.75 | CACNA1B (0.58) | CACNA1BGAAHTTATMMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7160887-B1 | Aromatic amine derivatives, their production and use | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2007-01-09 | — | — | US | disclosed |