Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1B | Q00975 | 12/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.42 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5205144 | 0.91 | CACNA1B (0.44) | CACNA1BLMNAMEN1KMT2A | |
| SCHEMBL5203690 | 0.82 | FFAR1 (0.47) | ALDH1A1KDM4CKDM5BLMNAMEN1 | |
| SCHEMBL5204934 | 0.81 | PTGES (0.39) | KDM4CKDM5BMEN1KMT2A | |
| SCHEMBL5205774 | 0.81 | ADAMTS5 (0.40) | ALDH1A1MEN1KMT2A | |
| SCHEMBL5205002 | 0.80 | CACNA1B (0.52) | CACNA1BALDH1A1LMNANPC1RAB9A | |
| SCHEMBL5201809 | 0.78 | FFAR1 (0.49) | CACNA1B | |
| SCHEMBL5206544 | 0.77 | MEN1 (0.45) | ALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL6174370 | 0.76 | CACNA1B (0.48) | CACNA1BALDH1A1KDM4CKDM5BLMNA | |
| SCHEMBL5202945 | 0.73 | ALDH1A1 (0.48) | ALDH1A1LMNANPC1RAB9AMEN1 | |
| SCHEMBL4019172 | 0.73 | MAPK14 (0.67) | LMNANPC1RAB9AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7160887-B1 | Aromatic amine derivatives, their production and use | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2007-01-09 | — | — | US | disclosed |