Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 3/20 | 0.42 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.40 |
| ▸ | CHRM4 | P08173 | 3/20 | 0.40 |
| ▸ | CHRM5 | P08912 | 3/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 5/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | NPY2R | P49146 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.36 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.36 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | OXTR | P30559 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5202866 | 0.77 | ACACB (0.41) | ACACBPTGER4CHRM4FFAR1GAA | |
| SCHEMBL5204575 | 0.74 | OPRM1 (0.47) | HTR2AOPRM1OPRK1OPRL1 | |
| SCHEMBL5204148 | 0.73 | HTR2A (0.47) | HTR2AOPRM1OPRK1OPRL1 | |
| SCHEMBL10263971 | 0.72 | OPRM1 (0.54) | OPRM1OPRK1OPRL1 | |
| SCHEMBL5201290 | 0.72 | ACACB (0.44) | ACACBPTGER4FFAR1HPGDHTR2A | |
| SCHEMBL5204586 | 0.70 | OPRM1 (0.47) | OPRM1OPRK1OPRL1 | |
| SCHEMBL5204015 | 0.70 | OPRM1 (0.47) | HTR2AOPRM1OPRK1OPRL1 | |
| SCHEMBL5201788 | 0.69 | OPRM1 (0.47) | HTR2AOPRM1OPRK1OPRL1 | |
| SCHEMBL5202790 | 0.69 | OPRM1 (0.50) | OPRM1OPRK1OPRL1 | |
| SCHEMBL5204378 | 0.69 | ACACB (0.42) | ACACBGAAHPGDSMN1; SMN2NPY2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1179532-B1 | PROCESS FOR THE PRODUCTION OF INDOLE DERIVATIVES AND INTERMEDIATES THEREFOR | EISAI R&D MAN CO LTD (JP) | 2007-06-13 | — | — | EP | disclosed |
| US-6573384-B1 | 1,4-substituted cyclic amine compound which is useful as a pharmaceutical, and an intermediate for the process | EISAI CO., LTD. (JP) | 2003-06-03 | — | — | US | disclosed |
| EP-1179532-A1 | PROCESS FOR THE PRODUCTION OF INDOLE DERIVATIVES AND INTERMEDIATES THEREFOR | Eisai Co., Ltd. (JP) | 2002-02-13 | — | — | EP | disclosed |