Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 4/20 | 0.44 |
| ▸ | NOS1 | P29475 | 1/20 | 0.41 |
| ▸ | NOS2 | P35228 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | NPY2R | P49146 | 1/20 | 0.38 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | PTGDR2 | Q9Y5Y4 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5201976 | 0.79 | OPRM1 (0.43) | ALDH1A1HSD17B10PTGDR2POLBKDM1A | |
| SCHEMBL5201971 | 0.74 | CACNA1G (0.44) | L3MBTL1ALDH1A1MAPK1NPSR1HSD17B10 | |
| SCHEMBL5205007 | 0.72 | ACACB (0.42) | ACACBHPGDNPY2RPTGER4FFAR1 | |
| SCHEMBL5202266 | 0.71 | CACNA1G (0.42) | ALDH1A1HSD17B10KDM1AHTR2A | |
| SCHEMBL5202866 | 0.71 | ACACB (0.41) | ACACBHPGDNPY2RPTGER4FFAR1 | |
| SCHEMBL4137101 | 0.69 | L3MBTL1 (0.54) | ACACBL3MBTL1MAPTNPC1ALDH1A1 | |
| SCHEMBL20521460 | 0.68 | TSHR (0.55) | L3MBTL1MAPTNPC1ALDH1A1LMNA | |
| SCHEMBL5203925 | 0.68 | CNR1 (0.43) | L3MBTL1ALDH1A1TSHRMAPK1HSD17B10 | |
| SCHEMBL5201178 | 0.67 | ALDH1A1 (0.44) | MAPTALDH1A1TSHRHSD17B10 | |
| SCHEMBL31341914 | 0.67 | PANK3 (0.43) | ACACBL3MBTL1MAPTALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1179532-B1 | PROCESS FOR THE PRODUCTION OF INDOLE DERIVATIVES AND INTERMEDIATES THEREFOR | EISAI R&D MAN CO LTD (JP) | 2007-06-13 | — | — | EP | disclosed |
| US-6573384-B1 | 1,4-substituted cyclic amine compound which is useful as a pharmaceutical, and an intermediate for the process | EISAI CO., LTD. (JP) | 2003-06-03 | — | — | US | disclosed |
| EP-1179532-A1 | PROCESS FOR THE PRODUCTION OF INDOLE DERIVATIVES AND INTERMEDIATES THEREFOR | Eisai Co., Ltd. (JP) | 2002-02-13 | — | — | EP | disclosed |