Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 5/20 | 0.41 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 5/20 | 0.37 |
| ▸ | NPY2R | P49146 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.34 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5205007 | 0.77 | ACACB (0.42) | ACACBPTGER4FFAR1NPY2RGAA | |
| SCHEMBL5204378 | 0.75 | ACACB (0.42) | ACACBNPY2RGAAHPGDSMN1; SMN2 | |
| SCHEMBL5206812 | 0.73 | SIGMAR1 (0.40) | PTGDR2HTR2A | |
| SCHEMBL5205196 | 0.72 | HTR2A (0.47) | HTR2A | |
| SCHEMBL5201290 | 0.71 | ACACB (0.44) | ACACBPTGER4FFAR1NPY2RPTGDR2 | |
| SCHEMBL5201956 | 0.70 | KCNH2 (0.43) | HTR2A | |
| SCHEMBL5206818 | 0.70 | KDM4E (0.36) | PTGDR2HPGD | |
| SCHEMBL5206821 | 0.69 | KDM4E (0.37) | HPGD | |
| SCHEMBL4137101 | 0.68 | L3MBTL1 (0.54) | ACACBNPY2RHPGDSMN1; SMN2 | |
| SCHEMBL5206815 | 0.67 | SLC22A12 (0.44) | SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1179532-B1 | PROCESS FOR THE PRODUCTION OF INDOLE DERIVATIVES AND INTERMEDIATES THEREFOR | EISAI R&D MAN CO LTD (JP) | 2007-06-13 | — | — | EP | disclosed |
| US-6573384-B1 | 1,4-substituted cyclic amine compound which is useful as a pharmaceutical, and an intermediate for the process | EISAI CO., LTD. (JP) | 2003-06-03 | — | — | US | disclosed |
| EP-1179532-A1 | PROCESS FOR THE PRODUCTION OF INDOLE DERIVATIVES AND INTERMEDIATES THEREFOR | Eisai Co., Ltd. (JP) | 2002-02-13 | — | — | EP | disclosed |