Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | IDO1 | P14902 | 1/20 | 0.43 |
| ▸ | CNR1 | P21554 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.41 |
| ▸ | FDFT1 | P37268 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5205241 | 0.84 | KDM4E (0.46) | LMNAMEN1KMT2AMAPTMAPK1 | |
| SCHEMBL25834083 | 0.78 | KDM4E (0.63) | LMNAMEN1KMT2AMAPTMAPK1 | |
| SCHEMBL6178811 | 0.78 | HPGD (0.51) | LMNAMEN1KMT2AMAPTNPC1 | |
| SCHEMBL5354570 | 0.77 | FDFT1 (0.57) | IDO1FDFT1 | |
| SCHEMBL5208318 | 0.77 | HDAC1 (0.43) | KDM4ECNR1SMN1; SMN2 | |
| SCHEMBL3064038 | 0.76 | ALDH1A1 (0.54) | LMNAMEN1KMT2AMAPTMAPK1 | |
| SCHEMBL21090366 | 0.76 | FDFT1 (0.47) | KDM4EIDO1CNR1FDFT1 | |
| SCHEMBL5204827 | 0.76 | TDP1 (0.41) | LMNAMEN1KMT2AMAPTL3MBTL1 | |
| SCHEMBL5202388 | 0.76 | CNR1 (0.40) | MEN1KMT2AMAPTKDM4ECNR1 | |
| SCHEMBL6175335 | 0.75 | TDP1 (0.47) | LMNAMEN1KMT2AMAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7160887-B1 | Aromatic amine derivatives, their production and use | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2007-01-09 | — | — | US | disclosed |
| EP-1123918-B1 | AROMATIC AMINE DERIVATIVES, PROCESS FOR THE PREPARATION THEREOF AND AGENTS CONTAINING THE SAME | TAKEDA PHARMACEUTICAL (JP) | 2005-03-09 | — | — | EP | disclosed |
| EP-1123918-A1 | AROMATIC AMINE DERIVATIVES, PROCESS FOR THE PREPARATION THEREOF AND AGENTS CONTAINING THE SAME | Takeda Chemical Industries, Ltd. (JP) | 2001-08-16 | — | — | EP | disclosed |