Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 2/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.36 |
| ▸ | FLT3 | P36888 | 5/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | CASP3 | P42574 | 1/20 | 0.34 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | MGAM | O43451 | 1/20 | 0.33 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.33 |
| ▸ | F10 | P00742 | 1/20 | 0.33 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL5207372 | 0.92 | RORC (0.47) | RORCKMT2ATAAR1FLT3NPC1 | |
| Trifluoroacetic Acid SCHEMBL5204002 | 0.89 | FLT3 (0.38) | RORCKMT2ATAAR1FLT3NPC1 | |
| Trifluoroacetic Acid SCHEMBL5209718 | 0.89 | FLT3 (0.39) | RORCKMT2ATAAR1FLT3NPC1 | |
| Trifluoroacetic Acid SCHEMBL5205740 | 0.89 | RORC (0.38) | RORCKMT2ATAAR1FLT3NPC1 | |
| Trifluoroacetic Acid SCHEMBL5211954 | 0.89 | FLT3 (0.37) | RORCKMT2ATAAR1FLT3NPC1 | |
| Trifluoroacetic Acid SCHEMBL5204823 | 0.87 | AMY1A (0.48) | RORCKMT2AFLT3NPC1RAB9A | |
| Trifluoroacetic Acid SCHEMBL5210994 | 0.87 | MAPT (0.43) | RORCKMT2ARAB9AMAPTALDH1A1 | |
| Trifluoroacetic Acid SCHEMBL5280152 | 0.87 | ALDH1A1 (0.40) | RORCCNR2KMT2AFLT3NPC1 | |
| Trifluoroacetic Acid SCHEMBL5208332 | 0.86 | FLT3 (0.35) | RORCKMT2AFLT3NPC1RAB9A | |
| Trifluoroacetic Acid SCHEMBL5628234 | 0.85 | ALDH1A1 (0.38) | RORCCNR2KMT2AFLT3NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1343561-B1 | SERINE PROTEASE INHIBITORS | TULARIK LTD (GB) | 2007-02-28 | — | — | EP | disclosed |