Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.43 |
| ▸ | POLB | P06746 | 4/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.42 |
| ▸ | HPGD | P15428 | 6/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.42 |
| ▸ | GAA | P10253 | 5/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.42 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 4/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL5207372 | 0.92 | RORC (0.47) | MAPTKMT2ARAB9ARORC | |
| Trifluoroacetic Acid SCHEMBL5204002 | 0.87 | FLT3 (0.38) | MAPTPOLBALDH1A1KDM4ENPSR1 | |
| Trifluoroacetic Acid SCHEMBL5204823 | 0.87 | AMY1A (0.48) | MAPTPOLBALDH1A1HPGDKDM4E | |
| Trifluoroacetic Acid SCHEMBL5209718 | 0.87 | FLT3 (0.39) | MAPTPOLBALDH1A1HPGDKDM4E | |
| Trifluoroacetic Acid SCHEMBL5205660 | 0.87 | RORC (0.38) | MAPTALDH1A1KDM4EHSD17B10MEN1 | |
| Trifluoroacetic Acid SCHEMBL5205740 | 0.87 | RORC (0.38) | MAPTPOLBALDH1A1NPSR1MEN1 | |
| Trifluoroacetic Acid SCHEMBL5211954 | 0.86 | FLT3 (0.37) | MAPTPOLBALDH1A1HPGDKDM4E | |
| Trifluoroacetic Acid SCHEMBL5280152 | 0.84 | ALDH1A1 (0.40) | MAPTALDH1A1HPGDKDM4EMEN1 | |
| Trifluoroacetic Acid SCHEMBL5208332 | 0.84 | FLT3 (0.35) | MAPTPOLBALDH1A1HPGDKDM4E | |
| Trifluoroacetic Acid SCHEMBL5628234 | 0.83 | ALDH1A1 (0.38) | MAPTALDH1A1HPGDKDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1343561-B1 | SERINE PROTEASE INHIBITORS | TULARIK LTD (GB) | 2007-02-28 | — | — | EP | disclosed |