Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | FAAH | O00519 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | P2RX3 | P56373 | 4/20 | 0.45 |
| ▸ | CHKA | P35790 | 1/20 | 0.44 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.43 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.42 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5201520 | 0.84 | ALDH1A1 (0.55) | MAPTGAAP2RX3TLR7MEN1 | |
| SCHEMBL24327920 | 0.78 | PDE4A (0.47) | MAPTRAB9ANPC1HTTMEN1 | |
| SCHEMBL24327508 | 0.76 | SMN1; SMN2 (0.46) | LMNAMAPTRAB9ANPC1HTT | |
| SCHEMBL11641243 | 0.75 | DRD2 (0.56) | GAAMEN1KMT2A | |
| SCHEMBL11643527 | 0.72 | LMNA (0.56) | LMNATP53MAPTLOXL2RAB9A | |
| SCHEMBL3534743 | 0.72 | LMNA (0.63) | LMNAMAPTHTTMEN1KMT2A | |
| SCHEMBL13199366 | 0.72 | HSP90AA1 (0.46) | LMNATP53MAPTLOXL2RAB9A | |
| SCHEMBL2414081 | 0.70 | MAPK10 (0.50) | LMNALOXL2RAB9ANPC1HTT | |
| SCHEMBL1058355 | 0.70 | HDAC1 (0.66) | HTT | |
| SCHEMBL11639310 | 0.70 | PTPN1 (0.60) | LMNAMAPTLOXL2RAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7279576-B2 | Anti-cancer medicaments | DECIPHERA PHARMACEUTICALS, LLC (US) | 2007-10-09 | — | — | US | disclosed |
| US-7279576-B2 | Anti-cancer medicaments | DECIPHERA PHARMACEUTICALS, LLC (US) | 2007-10-09 | — | — | US | disclosed |
| US-7279576-B2 | Anti-cancer medicaments | DECIPHERA PHARMACEUTICALS, LLC (US) | 2007-10-09 | — | — | US | disclosed |
| EP-1590344-A4 | ANTI-CANCER MEDICAMENTS | DECIPHERA PHARMACEUTICALS LLC (US) | 2007-08-29 | — | — | EP | disclosed |
| CN-1791596-A | Anti-cancer medicaments | DECIPHERA PHARMACEUTICALS LLC (US) | 2006-06-21 | — | — | CN | disclosed |
| EP-1590344-A2 | ANTI-CANCER MEDICAMENTS | Deciphera Pharmaceuticals, Inc. (US) | 2005-11-02 | — | — | EP | disclosed |
| US-20040176395-A1 | Anti-cancer medicaments | DECIPHERA PHARMACEUTICALS, LLC | 2004-09-09 | — | — | US | disclosed |
| WO-2004060305-A2 | ANTI-CANCER MEDICAMENTS | DECIPHERA PHARMACEUTICALS, LLC (US) | 2004-07-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040176395-A1 | Anti-cancer medicaments | ABL1, ABL2, SRC | LMNA 4092/4885TP53 4/4885MAPT 3631/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.