Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | P2RX3 | P56373 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24327425 | 0.86 | P2RX3 (0.47) | SMN1; SMN2KDM4EHDAC1HDAC8HDAC6 | |
| SCHEMBL24327920 | 0.85 | PDE4A (0.47) | SMN1; SMN2KMT2AMAPTNPC1HTT | |
| SCHEMBL24327423 | 0.80 | RGS4 (0.45) | CYP3A4CYP1A2GAACYP2C19KMT2A | |
| SCHEMBL24327921 | 0.80 | TRPV1 (0.48) | KMT2AP2RX3POLBHSD17B10TLR7 | |
| SCHEMBL24328735 | 0.78 | P2RX3 (0.44) | KDM4EHDAC1HDAC8HDAC6P2RX3 | |
| SCHEMBL24327512 | 0.77 | KIF11 (0.42) | SMN1; SMN2KDM4ECYP3A4CYP1A2CYP2C19 | |
| SCHEMBL24327426 | 0.77 | P2RX3 (0.44) | CYP2C19HDAC1HDAC8HDAC6P2RX3 | |
| SCHEMBL5205919 | 0.76 | LMNA (0.47) | GAAAGTR1KMT2AP2RX3MAPT | |
| SCHEMBL24327444 | 0.75 | CHRM5 (0.46) | P2RX3 | |
| SCHEMBL24327510 | 0.75 | RGS4 (0.52) | SMN1; SMN2CYP1A2KMT2AP2RX3MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022081984-A1 | METHODS AND COMPOUNDS TO TREAT SARS INFECTIONS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2022-04-21 | — | — | WO | disclosed |