Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 2/20 | 0.42 |
| ▸ | STS | P08842 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | KDM1A | O60341 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | CYP26A1 | O43174 | 2/20 | 0.38 |
| ▸ | CYP24A1 | Q07973 | 1/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
| ▸ | PPARD | Q03181 | 1/20 | 0.37 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.37 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20241215 | 0.91 | BRD4 (0.43) | MAOBKDM1AMAOACYP26A1CYP24A1 | |
| SCHEMBL30112223 | 0.84 | BRD4 (0.48) | MAOBSLC6A4BRD4CA1CA2 | |
| SCHEMBL31377693 | 0.80 | SLC6A4 (0.41) | MAOBSLC6A4MAOABRD4 | |
| SCHEMBL28620218 | 0.78 | CYP26A1 (0.43) | STSCYP26A1CYP24A1BRD4MAPT | |
| SCHEMBL22516964 | 0.76 | SLC6A4 (0.43) | SLC6A4MEN1MAPTKMT2AHSD17B10 | |
| SCHEMBL25694 | 0.76 | SLC6A4 (0.47) | SLC6A4KDM1A | |
| SCHEMBL18322124 | 0.75 | NPC1 (0.48) | CYP26A1CYP24A1BRD4NPC1RAB9A | |
| SCHEMBL1530209 | 0.74 | PPARD (0.45) | PPARDMEN1NPC1GAAMAPT | |
| SCHEMBL24495756 | 0.72 | SLC6A4 (0.40) | SLC6A4 | |
| SCHEMBL1530289 | 0.72 | APLNR (0.51) | CYP26A1CYP24A1PPARDL3MBTL1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1819670-B1 | 12-ARYL PROSTAGLANDIN ANALOGS | ALLERGAN INC (US) | 2012-08-08 | — | — | EP | disclosed |
| EP-1819670-A1 | 12-ARYL PROSTAGLANDIN ANALOGS | Allergan, Inc. (US) | 2007-08-22 | — | — | EP | disclosed |
| US-7091231-B2 | 12-Aryl prostaglandin analogs | ALLERGAN, INC. (US) | 2006-08-15 | — | — | US | disclosed |
| US-20060148894-A1 | Z)-7-{(1R,2S,3R)-2-[4-(Cyclohexyl-hydroxy-methyl)-phenyl]-3-hydroxy-5-oxo cyclopentyl}-hept-5-enoic acid methyl ester; treating vision defects | ALLERGAN, INC. (US) | 2006-07-06 | — | — | US | disclosed |
| WO-2006063179-A1 | 12-ARYL PROSTAGLANDIN ANALOGS | ALLERGAN, INC. (US) | 2006-06-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060148894-A1 | Z)-7-{(1R,2S,3R)-2-[4-(Cyclohexyl-hydroxy-methyl)-phenyl]-3-hydroxy-5-oxo cyclopentyl}-hept-5-enoic acid methyl ester; treating vision defects | ALOX5, PTGER2, PTGER1 | MAOB 1378/4885STS 3189/4885SLC6A4 3019/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.