Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | SDCBP | O00560 | 1/20 | 0.38 |
| ▸ | SDC2 | P34741 | 1/20 | 0.38 |
| ▸ | LPAR1 | Q92633 | 3/20 | 0.38 |
| ▸ | LPAR5 | Q9H1C0 | 3/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | TSPO | P30536 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | FAAH | O00519 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5204311 | 0.93 | ALDH1A1 (0.42) | HDAC1ALDH1A1SDCBPSDC2LPAR1 | |
| SCHEMBL5202464 | 0.88 | ALDH1A1 (0.41) | HDAC1ALDH1A1TSPOPTPN1HTT | |
| SCHEMBL5204889 | 0.88 | HDAC1 (0.47) | HDAC1ALDH1A1SDCBPSDC2TSPO | |
| SCHEMBL5204997 | 0.87 | ALDH1A1 (0.43) | HDAC1ALDH1A1LPAR1LPAR5TSPO | |
| SCHEMBL5206214 | 0.86 | ALDH1A1 (0.40) | HDAC1ALDH1A1SDCBPSDC2KMT2A | |
| Hydrochloric Acid SCHEMBL5205960 | 0.86 | LPAR1 (0.41) | ALDH1A1LPAR1LPAR5TSPOKMT2A | |
| SCHEMBL5203418 | 0.85 | ALDH1A1 (0.40) | HDAC1ALDH1A1SDCBPSDC2TSPO | |
| SCHEMBL5204960 | 0.81 | HTT (0.37) | ALDH1A1TSPOKMT2AHTTSMN1; SMN2 | |
| SCHEMBL5208000 | 0.80 | HDAC1 (0.44) | HDAC1SDCBPSDC2TDP1TSPO | |
| Hydrochloric Acid SCHEMBL5203571 | 0.80 | SSTR5 (0.43) | ALDH1A1LPAR1LPAR5TSPOKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7160887-B1 | Aromatic amine derivatives, their production and use | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2007-01-09 | — | — | US | disclosed |
| EP-1123918-B1 | AROMATIC AMINE DERIVATIVES, PROCESS FOR THE PREPARATION THEREOF AND AGENTS CONTAINING THE SAME | TAKEDA PHARMACEUTICAL (JP) | 2005-03-09 | — | — | EP | disclosed |
| EP-1123918-A1 | AROMATIC AMINE DERIVATIVES, PROCESS FOR THE PREPARATION THEREOF AND AGENTS CONTAINING THE SAME | Takeda Chemical Industries, Ltd. (JP) | 2001-08-16 | — | — | EP | disclosed |