Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.45 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.44 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.44 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | GFER | P55789 | 1/20 | 0.44 |
| ▸ | CASP6 | P55212 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | GUSB | P08236 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5207567 | 0.89 | KDM4E (0.47) | MAPTALDH1A1KDM4ENPC1RAB9A | |
| SCHEMBL5202505 | 0.88 | ALDH1A1 (0.59) | MAPTALDH1A1KDM4ENPC1RAB9A | |
| SCHEMBL5203249 | 0.81 | S1PR1 (0.61) | MAPTALDH1A1KDM4ENPC1RAB9A | |
| SCHEMBL5206623 | 0.80 | NPC1 (0.68) | MAPTALDH1A1KDM4ENPC1RAB9A | |
| SCHEMBL21760737 | 0.79 | NPC1 (0.66) | KDM4ENPC1RAB9ANR1H4S1PR1 | |
| SCHEMBL5202688 | 0.79 | MYC (0.58) | MAPTALDH1A1KDM4ENPC1RAB9A | |
| SCHEMBL5204029 | 0.77 | NPC1 (0.64) | MAPTALDH1A1NPC1RAB9ATHRB | |
| SCHEMBL1505169 | 0.76 | MYC (0.58) | MAPTALDH1A1KDM4ENPC1RAB9A | |
| SCHEMBL968770 | 0.76 | NPC1 (0.66) | MAPTALDH1A1KDM4ENPC1RAB9A | |
| SCHEMBL968281 | 0.76 | MYC (0.58) | MAPTALDH1A1KDM4ENPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7223791-B2 | Function regulator for retinoid relative receptor | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2007-05-29 | — | — | US | disclosed |
| US-20040157881-A1 | Function regulator for retinoid relative receptor | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2004-08-12 | — | — | US | disclosed |
| EP-1405636-A1 | FUNCTION REGULATOR FOR RETINOID RELATIVE RECEPTOR | Takeda Chemical Industries, Ltd. (JP) | 2004-04-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040157881-A1 | Function regulator for retinoid relative receptor | RXRA, RARA, RARG | MAPT 4855/4885ALDH1A1 700/4885KDM4E 2371/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.