Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | LPAR1 | Q92633 | 15/20 | 0.44 |
| ▸ | LPAR5 | Q9H1C0 | 15/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5202945 | 0.80 | ALDH1A1 (0.48) | MEN1KMT2AHTTL3MBTL1LPAR1 | |
| SCHEMBL14674364 | 0.77 | LPAR1 (0.46) | MEN1KMT2AHTTL3MBTL1LPAR1 | |
| SCHEMBL5205589 | 0.77 | CACNA1B (0.50) | MEN1KMT2AALDH1A1LMNA | |
| SCHEMBL8773482 | 0.76 | MEN1 (0.69) | MEN1KMT2AHTTL3MBTL1ALDH1A1 | |
| SCHEMBL14674405 | 0.76 | LPAR1 (0.47) | LPAR1LPAR5 | |
| SCHEMBL2209892 | 0.75 | HTT (0.51) | MEN1KMT2AHTTL3MBTL1ALDH1A1 | |
| SCHEMBL5205267 | 0.75 | MEN1 (0.41) | MEN1KMT2AHTTL3MBTL1LPAR1 | |
| SCHEMBL335254 | 0.75 | MEN1 (0.50) | MEN1KMT2AHTTL3MBTL1ALDH1A1 | |
| SCHEMBL5201785 | 0.75 | MAPK13 (0.54) | MEN1KMT2AHTTL3MBTL1ALDH1A1 | |
| SCHEMBL5206121 | 0.74 | MEN1 (0.41) | MEN1KMT2AHTTL3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7160887-B1 | Aromatic amine derivatives, their production and use | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2007-01-09 | — | — | US | disclosed |