Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.32 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | KDM1A | O60341 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5207205 | 0.98 | ALDH1A1 (0.33) | ALDH1A1TP53KDM1A | |
| SCHEMBL14858388 | 0.81 | ALDH1A1 (0.40) | ALDH1A1TP53TSHRCYP2C19MEN1 | |
| SCHEMBL5332707 | 0.79 | ALDH1A1 (0.38) | ALDH1A1TP53TSHRCYP2C19KDM1A | |
| SCHEMBL14061763 | 0.77 | KDM1A (0.35) | ALDH1A1TP53TSHRCYP2C19KDM1A | |
| SCHEMBL3296902 | 0.75 | PPIA (0.32) | TSHRPOLB | |
| SCHEMBL25435115 | 0.74 | ALDH1A1 (0.38) | ALDH1A1TP53TSHRKDM1APOLB | |
| SCHEMBL234076 | 0.74 | ALDH1A1 (0.41) | ALDH1A1TP53TSHRCYP2C19POLB | |
| SCHEMBL6730674 | 0.74 | CA2 (0.41) | ALDH1A1TP53CYP2C19 | |
| Hydrochloric Acid SCHEMBL6732984 | 0.73 | CA2 (0.39) | CYP2C19POLB | |
| SCHEMBL21265902 | 0.73 | SMN1; SMN2 (0.38) | MEN1KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1758891-A2 | BENZIMIDAZOLONE CARBOXYLIC ACID DERIVATIVES | Pfizer Japan Inc. (JP) | 2007-03-07 | — | — | EP | disclosed |
| WO-2005123718-A2 | BENZIMIDAZOLONE CARBOXYLIC ACID DERIVATIVES | PFIZER JAPAN INC. (JP) | 2005-12-29 | — | — | WO | disclosed |