Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | KDM1A | O60341 | 1/20 | 0.32 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5206583 | 0.98 | ALDH1A1 (0.33) | ALDH1A1KDM1ATP53 | |
| SCHEMBL5332707 | 0.81 | ALDH1A1 (0.38) | ALDH1A1KDM1AAKR1C1TP53FFAR3 | |
| SCHEMBL14858388 | 0.79 | ALDH1A1 (0.40) | ALDH1A1TP53 | |
| SCHEMBL14061763 | 0.78 | KDM1A (0.35) | ALDH1A1KDM1ATP53FFAR3 | |
| SCHEMBL25435115 | 0.76 | ALDH1A1 (0.38) | ALDH1A1KDM1ATP53FFAR3 | |
| SCHEMBL3292584 | 0.74 | PPIA (0.33) | — | |
| SCHEMBL21265902 | 0.74 | SMN1; SMN2 (0.38) | — | |
| SCHEMBL6138350 | 0.73 | ALDH1A1 (0.39) | ALDH1A1TP53FFAR3 | |
| SCHEMBL3296902 | 0.73 | PPIA (0.32) | — | |
| SCHEMBL5323192 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1758891-A2 | BENZIMIDAZOLONE CARBOXYLIC ACID DERIVATIVES | Pfizer Japan Inc. (JP) | 2007-03-07 | — | — | EP | disclosed |
| WO-2005123718-A2 | BENZIMIDAZOLONE CARBOXYLIC ACID DERIVATIVES | PFIZER JAPAN INC. (JP) | 2005-12-29 | — | — | WO | disclosed |