Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 12/20 | 0.35 |
| ▸ | OPRD1 | P41143 | 12/20 | 0.35 |
| ▸ | TPSAB1 | Q15661 | 3/20 | 0.33 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | DPP4 | P27487 | 1/20 | 0.32 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL5210556 | 0.86 | CXCR2 (0.43) | OPRM1OPRD1LMNA | |
| Trifluoroacetic Acid SCHEMBL5210732 | 0.85 | MAPT (0.35) | FOLH1LMNATP53MAPTHPGD | |
| Trifluoroacetic Acid SCHEMBL5207834 | 0.83 | PDE4D (0.41) | LMNATP53MAPTHPGDMAPK1 | |
| Trifluoroacetic Acid SCHEMBL5206983 | 0.83 | MAPT (0.41) | LMNATP53MAPTHPGDTSHR | |
| Trifluoroacetic Acid SCHEMBL5208680 | 0.83 | KDM4E (0.36) | OPRM1OPRD1FOLH1LMNATP53 | |
| Trifluoroacetic Acid SCHEMBL5209515 | 0.81 | MAPT (0.40) | OPRM1OPRD1FOLH1LMNATP53 | |
| Trifluoroacetic Acid SCHEMBL5207793 | 0.81 | PDE4D (0.40) | LMNATP53MAPTHPGDMAPK1 | |
| Trifluoroacetic Acid SCHEMBL5206475 | 0.81 | PTGER4 (0.34) | LMNATP53MAPT | |
| Trifluoroacetic Acid SCHEMBL5209084 | 0.81 | MAPT (0.32) | FOLH1LMNATP53MAPTHTT | |
| Trifluoroacetic Acid SCHEMBL5217152 | 0.79 | ALDH1A1 (0.37) | LMNATP53MAPTHPGDHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1343561-B1 | SERINE PROTEASE INHIBITORS | TULARIK LTD (GB) | 2007-02-28 | — | — | EP | disclosed |