Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 12/20 | 0.38 |
| ▸ | NMT2 | O60551 | 1/20 | 0.37 |
| ▸ | NMT1 | P30419 | 1/20 | 0.37 |
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.37 |
| ▸ | CDC25A | P30304 | 1/20 | 0.35 |
| ▸ | CDC25B | P30305 | 1/20 | 0.35 |
| ▸ | CDC25C | P30307 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5207713 | 0.83 | MAPK14 (0.44) | MAPK14 | |
| SCHEMBL5204460 | 0.81 | NMT2 (0.40) | MAPK14NMT2NMT1PCSK9CDC25A | |
| SCHEMBL5207326 | 0.78 | MAOB (0.38) | MAPK14 | |
| SCHEMBL5207452 | 0.77 | MEN1 (0.39) | MAPK14 | |
| SCHEMBL5205590 | 0.69 | MAOB (0.39) | MAPK14 | |
| SCHEMBL5202380 | 0.69 | MAOB (0.42) | MAPK14 | |
| SCHEMBL5236197 | 0.69 | MAPK14 (0.41) | MAPK14NMT2NMT1 | |
| SCHEMBL5240413 | 0.69 | NMT2 (0.42) | MAPK14NMT2NMT1 | |
| SCHEMBL5203740 | 0.68 | CYP1A1 (0.42) | MAPK14 | |
| SCHEMBL3523048 | 0.67 | MAPK14 (0.39) | MAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1802590-A1 | SUBSTITUTED N-ALKYLPYRIMIDINONES | Pharmacia & Upjohn Company LLC (US) | 2007-07-04 | — | — | EP | disclosed |
| WO-2006040666-A1 | SUBSTITUTED N-ALKYLPYRIMIDINONES | PHARMACIA & UPJOHN COMPANY LLC (US) | 2006-04-20 | — | — | WO | disclosed |