Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IP6K1 | Q92551 | 2/20 | 0.57 |
| ▸ | IP6K3 | Q96PC2 | 2/20 | 0.57 |
| ▸ | IP6K2 | Q9UHH9 | 2/20 | 0.57 |
| ▸ | NPC1 | O15118 | 3/20 | 0.54 |
| ▸ | RAB9A | P51151 | 3/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.54 |
| ▸ | TP53 | P04637 | 2/20 | 0.54 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.54 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.54 |
| ▸ | RELA | Q04206 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | NR1H4 | Q96RI1 | 3/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | MAOA | P21397 | 1/20 | 0.51 |
| ▸ | BLVRB | P30043 | 1/20 | 0.51 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.51 |
| ▸ | CA2 | P00918 | 2/20 | 0.51 |
| ▸ | CA9 | Q16790 | 2/20 | 0.51 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.51 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5207218 | 0.89 | MCHR1 (0.60) | IP6K1IP6K3IP6K2NR1H4MAOA | |
| SCHEMBL12171136 | 0.89 | MCHR1 (0.60) | IP6K1IP6K3IP6K2NR1H4MAOA | |
| SCHEMBL5202240 | 0.88 | MAPT (0.63) | NPC1RAB9ASMN1; SMN2TP53NFKB1 | |
| SCHEMBL13417180 | 0.83 | NPC1 (0.75) | NPC1RAB9ASMN1; SMN2TP53NFKB1 | |
| SCHEMBL3675564 | 0.83 | NR1H4 (0.72) | NPC1RAB9ASMN1; SMN2TP53NFKB1 | |
| SCHEMBL12171112 | 0.83 | NR1H4 (0.72) | NPC1RAB9ASMN1; SMN2TP53NFKB1 | |
| SCHEMBL12171366 | 0.82 | NPC1 (0.78) | NPC1RAB9ASMN1; SMN2TP53NFKB1 | |
| SCHEMBL12171782 | 0.82 | NPC1 (0.70) | IP6K1IP6K3IP6K2NPC1RAB9A | |
| SCHEMBL59247 | 0.81 | RAB9A (0.72) | NPC1RAB9ASMN1; SMN2TP53NFKB1 | |
| SCHEMBL60427 | 0.81 | NPC1 (0.76) | NPC1RAB9ASMN1; SMN2TP53NFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7223791-B2 | Function regulator for retinoid relative receptor | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2007-05-29 | — | — | US | disclosed |
| US-20040157881-A1 | Function regulator for retinoid relative receptor | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2004-08-12 | — | — | US | disclosed |
| EP-1405636-A1 | FUNCTION REGULATOR FOR RETINOID RELATIVE RECEPTOR | Takeda Chemical Industries, Ltd. (JP) | 2004-04-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040157881-A1 | Function regulator for retinoid relative receptor | RXRA, RARA, RARG | IP6K1 1364/4885IP6K3 1983/4885IP6K2 1557/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.