Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 2/20 | 0.60 |
| ▸ | NR1H4 | Q96RI1 | 4/20 | 0.59 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.58 |
| ▸ | MAOA | P21397 | 1/20 | 0.58 |
| ▸ | MAOB | P27338 | 1/20 | 0.58 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.55 |
| ▸ | IP6K1 | Q92551 | 1/20 | 0.54 |
| ▸ | IP6K3 | Q96PC2 | 1/20 | 0.54 |
| ▸ | IP6K2 | Q9UHH9 | 1/20 | 0.54 |
| ▸ | ACACB | O00763 | 5/20 | 0.54 |
| ▸ | PPARD | Q03181 | 2/20 | 0.54 |
| ▸ | PPARA | Q07869 | 2/20 | 0.54 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.52 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12171136 | 1.00 | MCHR1 (0.60) | MCHR1NR1H4S1PR1MAOAMAOB | |
| SCHEMBL5207215 | 0.89 | IP6K1 (0.57) | MCHR1NR1H4S1PR1MAOAIP6K1 | |
| SCHEMBL20968252 | 0.89 | TPH1 (0.54) | MCHR1NR1H4S1PR1MAOAMAOB | |
| SCHEMBL3675564 | 0.88 | NR1H4 (0.72) | NR1H4S1PR1 | |
| SCHEMBL20968213 | 0.88 | NR1H4 (0.73) | MCHR1NR1H4S1PR1MAOAMAOB | |
| SCHEMBL12171112 | 0.88 | NR1H4 (0.72) | NR1H4S1PR1 | |
| SCHEMBL5204182 | 0.87 | MCHR1 (0.62) | MCHR1NR1H4S1PR1MAOAMAOB | |
| SCHEMBL3057263 | 0.85 | NR1H4 (0.61) | MCHR1NR1H4S1PR1MAOAMAOB | |
| SCHEMBL1430356 | 0.84 | NR1H4 (0.73) | NR1H4S1PR1 | |
| SCHEMBL20968234 | 0.82 | NR1H4 (0.61) | MCHR1NR1H4S1PR1MAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7223791-B2 | Function regulator for retinoid relative receptor | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2007-05-29 | — | — | US | disclosed |
| US-20040157881-A1 | Function regulator for retinoid relative receptor | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2004-08-12 | — | — | US | disclosed |
| EP-1405636-A1 | FUNCTION REGULATOR FOR RETINOID RELATIVE RECEPTOR | Takeda Chemical Industries, Ltd. (JP) | 2004-04-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040157881-A1 | Function regulator for retinoid relative receptor | RXRA, RARA, RARG | MCHR1 223/4885NR1H4 26/4885S1PR1 1456/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.