Trifluoroacetic Acid

Trifluoroacetic Acid

SCHEMBL5207332

NCc1cccc(Oc2ccccc2N(Cc2ccccc2)C(=O)CCC(=O)NCc2ccccc2)c1.O=C(O)C(F)(F)F

nearest known ligand 0.44

Full drug profile on Sugi Atlas →

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
TPSAB1 Q15661 3/20 0.44
LOX P28300 2/20 0.41
LOXL2 Q9Y4K0 2/20 0.41
KMT2A Q03164 2/20 0.41
MEN1 O00255 1/20 0.41
MAPK1 P28482 1/20 0.41
ALDH1A1 P00352 2/20 0.39
TSHR P16473 1/20 0.38
RECQL P46063 1/20 0.38
HTR2C P28335 1/20 0.38
TSPO P30536 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Trifluoroacetic Acid SCHEMBL5205999 0.94 ALDH1A1 (0.46) TPSAB1KMT2AMEN1ALDH1A1TSHR
Trifluoroacetic Acid SCHEMBL5202498 0.93 EPHX2 (0.38) TPSAB1ALDH1A1TSPO
Trifluoroacetic Acid SCHEMBL5205308 0.93 TPSAB1 (0.38) TPSAB1LOXLOXL2KMT2AMEN1
Trifluoroacetic Acid SCHEMBL5205473 0.93 TPSAB1 (0.39) TPSAB1LOXLOXL2KMT2AMEN1
Trifluoroacetic Acid SCHEMBL5204427 0.93 ALDH1A1 (0.41) TPSAB1KMT2AMEN1MAPK1ALDH1A1
Trifluoroacetic Acid SCHEMBL5205888 0.93 ALDH1A1 (0.37) TPSAB1LOXLOXL2KMT2AMEN1
Trifluoroacetic Acid SCHEMBL5201994 0.92 CYP3A4 (0.42) LOXLOXL2KMT2AMEN1MAPK1
Trifluoroacetic Acid SCHEMBL5205240 0.91 MAPK14 (0.39) TPSAB1ALDH1A1TSPO
Trifluoroacetic Acid SCHEMBL5202054 0.90 TSPO (0.39) TPSAB1TSPO
Trifluoroacetic Acid SCHEMBL5206020 0.90 ALDH1A1 (0.43) TPSAB1KMT2AMEN1ALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7160887-B1 Aromatic amine derivatives, their production and use TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2007-01-09 US disclosed
EP-1123918-B1 AROMATIC AMINE DERIVATIVES, PROCESS FOR THE PREPARATION THEREOF AND AGENTS CONTAINING THE SAME TAKEDA PHARMACEUTICAL (JP) 2005-03-09 EP disclosed
EP-1123918-A1 AROMATIC AMINE DERIVATIVES, PROCESS FOR THE PREPARATION THEREOF AND AGENTS CONTAINING THE SAME Takeda Chemical Industries, Ltd. (JP) 2001-08-16 EP disclosed