Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 2/20 | 0.51 |
| ▸ | RXRA | P19793 | 6/20 | 0.50 |
| ▸ | RXRB | P28702 | 6/20 | 0.50 |
| ▸ | RXRG | P48443 | 5/20 | 0.50 |
| ▸ | IKBKB | O14920 | 2/20 | 0.45 |
| ▸ | FAAH | O00519 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | ADK | P55263 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5211980 | 0.94 | RXRA (0.49) | NR4A2RXRARXRBRXRGIKBKB | |
| SCHEMBL5210892 | 0.90 | RXRA (0.62) | NR4A2RXRARXRBRXRGKDM4E | |
| SCHEMBL5213550 | 0.89 | TP53 (0.44) | NR4A2RXRARXRBRXRGIKBKB | |
| SCHEMBL5211085 | 0.88 | NR4A2 (0.42) | NR4A2RXRARXRBRXRGIKBKB | |
| SCHEMBL5212957 | 0.86 | IKBKB (0.47) | IKBKBKDM4EMEN1KMT2APTGDR2 | |
| SCHEMBL5211557 | 0.85 | RXRA (0.56) | NR4A2RXRARXRBRXRGKDM4E | |
| SCHEMBL5211537 | 0.84 | RXRA (0.47) | RXRARXRBRXRGFAAHKCNH2 | |
| SCHEMBL5215419 | 0.83 | RXRA (0.54) | NR4A2RXRARXRBRXRGKDM4E | |
| SCHEMBL5211453 | 0.82 | ALDH1A1 (0.41) | NR4A2RXRARXRBRXRGKDM4E | |
| SCHEMBL5210708 | 0.82 | NR4A2 (0.51) | NR4A2RXRARXRBRXRGKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7183276-B2 | Azole compounds | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2007-02-27 | — | — | US | disclosed |
| US-20050090534-A1 | Azole compounds | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2005-04-28 | — | — | US | disclosed |
| EP-1486490-A1 | AZOLE COMPOUNDS | Takeda Chemical Industries, Ltd. (JP) | 2004-12-15 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050090534-A1 | Azole compounds | AHR, NR0B2, NR2C2 | NR4A2 18/4885RXRA 1231/4885RXRB 1269/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.