Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IKBKB | O14920 | 2/20 | 0.47 |
| ▸ | TARBP2 | Q15633 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.44 |
| ▸ | KDR | P35968 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | PDCD4 | Q53EL6 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | CETP | P11597 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5212252 | 0.89 | MAPT (0.47) | IKBKBTARBP2SMN1; SMN2NPC1RAB9A | |
| SCHEMBL5207385 | 0.86 | NR4A2 (0.51) | IKBKBPTGDR2ALDH1A1HPGDMAPT | |
| SCHEMBL5213550 | 0.85 | TP53 (0.44) | IKBKBTARBP2SMN1; SMN2NPC1RAB9A | |
| SCHEMBL13116220 | 0.82 | PTGDR2 (0.58) | TARBP2SMN1; SMN2NPC1RAB9APTGDR2 | |
| SCHEMBL5211085 | 0.82 | NR4A2 (0.42) | IKBKBPTGDR2MAPTMEN1KMT2A | |
| SCHEMBL5211980 | 0.80 | RXRA (0.49) | IKBKBPTGDR2ALDH1A1HPGDMEN1 | |
| SCHEMBL13116169 | 0.79 | TARBP2 (0.56) | TARBP2SMN1; SMN2NPC1RAB9APTGDR2 | |
| SCHEMBL5211537 | 0.78 | RXRA (0.47) | TARBP2KDRALDH1A1MAPTLMNA | |
| SCHEMBL5209458 | 0.77 | LMNA (0.44) | TARBP2SMN1; SMN2NPC1RAB9AALDH1A1 | |
| SCHEMBL8303347 | 0.77 | NR4A2 (0.35) | IKBKBTARBP2PTGDR2ALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7183276-B2 | Azole compounds | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2007-02-27 | — | — | US | disclosed |
| US-20050090534-A1 | Azole compounds | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2005-04-28 | — | — | US | disclosed |
| EP-1486490-A1 | AZOLE COMPOUNDS | Takeda Chemical Industries, Ltd. (JP) | 2004-12-15 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050090534-A1 | Azole compounds | AHR, NR0B2, NR2C2 | IKBKB 2901/4885TARBP2 2702/4885SMN1; SMN2 584/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.