Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VCP | P55072 | 4/20 | 0.43 |
| ▸ | STK4 | Q13043 | 1/20 | 0.39 |
| ▸ | STK3 | Q13188 | 1/20 | 0.39 |
| ▸ | ACP1 | P24666 | 2/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.36 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.34 |
| ▸ | IDO1 | P14902 | 1/20 | 0.34 |
| ▸ | PFKFB3 | Q16875 | 1/20 | 0.34 |
| ▸ | KIT | P10721 | 1/20 | 0.33 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | DPP4 | P27487 | 1/20 | 0.32 |
| ▸ | KDM1A | O60341 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | IGF1R | P08069 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5202652 | 0.78 | GBA1 (0.51) | VCPSTK4STK3 | |
| SCHEMBL5207254 | 0.78 | STK4 (0.42) | VCPSTK4STK3ACP1IDO1 | |
| SCHEMBL5204673 | 0.73 | VCP (0.46) | VCPCHRM1CHRM2CHRM4CHRM3 | |
| SCHEMBL27776222 | 0.72 | GABRA1 (0.46) | ACP1CHRM1CHRM2CHRM4CHRM3 | |
| Hydrochloric Acid SCHEMBL311446 | 0.71 | GABRA1 (0.45) | ACP1CHRM1CHRM2CHRM4CHRM3 | |
| SCHEMBL5207246 | 0.69 | RAB9A (0.53) | VCPKITCNR2KDM1AMAOB | |
| SCHEMBL90906 | 0.67 | HSD11B1 (0.39) | STK4STK3CHRM1CHRM3PFKFB3 | |
| SCHEMBL5205206 | 0.66 | CKS1B (0.49) | VCP | |
| SCHEMBL5206599 | 0.65 | GBA1 (0.48) | VCPCNR2 | |
| SCHEMBL5207569 | 0.65 | KMT2A (0.41) | VCPIDO1CNR2IGF1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1306085-B1 | 2-Cyclohexyl-4-phenyl-1H-imidazole derivatives as ligands for the neuropeptide Y5 receptor | NEUROGEN CORP (US) | 2007-02-14 | — | — | EP | claimed |