Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | SOAT2 | O75908 | 1/20 | 0.36 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.36 |
| ▸ | FAAH | O00519 | 4/20 | 0.36 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.36 |
| ▸ | MGLL | Q99685 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | MMP2 | P08253 | 2/20 | 0.34 |
| ▸ | F7 | P08709 | 2/20 | 0.34 |
| ▸ | F3 | P13726 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | ECE1 | P42892 | 1/20 | 0.34 |
| ▸ | SGMS1 | Q86VZ5 | 1/20 | 0.34 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.34 |
| ▸ | MUS81 | Q96NY9 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5206903 | 0.84 | F7 (0.46) | SOAT2SOAT1FAAHKDM4EEPHX2 | |
| SCHEMBL5204911 | 0.81 | — | — | |
| SCHEMBL5207094 | 0.79 | PPARA (0.35) | CYP2D6SOAT2SOAT1FAAHTRPV1 | |
| SCHEMBL10661017 | 0.78 | KCNH2 (0.42) | KDM4ELMNAHSD17B10 | |
| SCHEMBL6558277 | 0.78 | KCNH2 (0.42) | KDM4ELMNAHSD17B10 | |
| SCHEMBL25065 | 0.78 | KCNH2 (0.42) | KDM4ELMNAHSD17B10 | |
| SCHEMBL5207607 | 0.78 | L3MBTL1 (0.34) | SOAT2SOAT1FAAHTRPV1MGLL | |
| SCHEMBL5207595 | 0.78 | L3MBTL1 (0.34) | SOAT2SOAT1FAAHTRPV1MGLL | |
| SCHEMBL24998 | 0.74 | KDM4E (0.35) | KDM4ELMNA | |
| SCHEMBL5209886 | 0.74 | CYP2D6 (0.42) | CYP2D6SOAT2SOAT1FAAHTRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0980867-B1 | KETONE DERIVATIVES AND MEDICINAL USE THEREOF | TORAY INDUSTRIES (JP) | 2007-08-08 | — | — | EP | disclosed |
| US-6100292-A | Ketone derivatives and their medical applications | TORAY INDUSTRIES, INC. (JP) | 2000-08-08 | — | — | US | disclosed |
| EP-0980867-A1 | KETONE DERIVATIVES AND MEDICINAL USE THEREOF | TORAY INDUSTRIES, INC. (JP) | 2000-02-23 | — | — | EP | disclosed |