Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 2/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | POLM | Q9NP87 | 1/20 | 0.35 |
| ▸ | POLK | Q9UBT6 | 1/20 | 0.35 |
| ▸ | POLL | Q9UGP5 | 1/20 | 0.35 |
| ▸ | POLH | Q9Y253 | 1/20 | 0.35 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.35 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.35 |
| ▸ | SOAT2 | O75908 | 1/20 | 0.34 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 2/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
| ▸ | FAAH | O00519 | 3/20 | 0.33 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5206377 | 0.82 | GABRA1 (0.39) | PTGS2TRPV1EPHX2 | |
| SCHEMBL5206903 | 0.80 | F7 (0.46) | SOAT2SOAT1FAAHEPHX2 | |
| SCHEMBL5207099 | 0.80 | EGFR (0.36) | PPARAPOLMPOLKPOLLPOLH | |
| SCHEMBL5207092 | 0.80 | EGFR (0.36) | PPARAPOLMPOLKPOLLPOLH | |
| SCHEMBL5207602 | 0.79 | CYP2D6 (0.37) | CYP2D6SOAT2SOAT1FAAHTRPV1 | |
| SCHEMBL6050423 | 0.75 | MEN1 (0.40) | PPARG | |
| SCHEMBL8798012 | 0.73 | ALDH1A1 (0.41) | CYP2D6 | |
| SCHEMBL7040556 | 0.72 | ALDH1A1 (0.44) | CYP2D6 | |
| SCHEMBL5207708 | 0.71 | CYP2D6 (0.42) | CYP2D6SOAT2SOAT1FAAHTRPV1 | |
| SCHEMBL5207917 | 0.71 | CYP2D6 (0.42) | CYP2D6SOAT2SOAT1FAAHTRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0980867-B1 | KETONE DERIVATIVES AND MEDICINAL USE THEREOF | TORAY INDUSTRIES (JP) | 2007-08-08 | — | — | EP | disclosed |
| US-6100292-A | Ketone derivatives and their medical applications | TORAY INDUSTRIES, INC. (JP) | 2000-08-08 | — | — | US | disclosed |
| EP-0980867-A1 | KETONE DERIVATIVES AND MEDICINAL USE THEREOF | TORAY INDUSTRIES, INC. (JP) | 2000-02-23 | — | — | EP | disclosed |