Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A2 | P31213 | 3/20 | 0.59 |
| ▸ | RXRA | P19793 | 1/20 | 0.54 |
| ▸ | RXRB | P28702 | 1/20 | 0.54 |
| ▸ | RXRG | P48443 | 1/20 | 0.54 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.54 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.48 |
| ▸ | CES2 | O00748 | 1/20 | 0.47 |
| ▸ | CES1 | P23141 | 1/20 | 0.47 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.47 |
| ▸ | NQO2 | P16083 | 1/20 | 0.47 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.45 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.45 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | MAP2K4 | P45985 | 2/20 | 0.45 |
| ▸ | MAPK6 | Q16659 | 2/20 | 0.45 |
| ▸ | MAPKAPK3 | Q16644 | 1/20 | 0.45 |
| ▸ | MAPKAPK5 | Q8IW41 | 1/20 | 0.45 |
| ▸ | P2RY14 | Q15391 | 2/20 | 0.44 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL505133 | 0.82 | SRD5A2 (0.77) | SRD5A2RXRARXRBRXRGCYP2C8 | |
| Hydrochloric Acid SCHEMBL5313295 | 0.81 | SRD5A2 (0.74) | SRD5A2RXRARXRBRXRGCYP2C8 | |
| Ethane SCHEMBL10971565 | 0.80 | SRD5A2 (0.80) | SRD5A2RXRARXRBRXRGCYP2C8 | |
| SCHEMBL1330891 | 0.80 | SRD5A2 (0.87) | SRD5A2RXRARXRBRXRGCYP2C8 | |
| SCHEMBL78879 | 0.80 | SRD5A2 (0.87) | SRD5A2RXRARXRBRXRGCYP2C8 | |
| SCHEMBL5204511 | 0.80 | MAPT (0.53) | BACE1 | |
| SCHEMBL23521062 | 0.78 | SRD5A2 (0.83) | SRD5A2RXRARXRBRXRGCYP2C8 | |
| SCHEMBL29208531 | 0.78 | SRD5A2 (0.83) | SRD5A2RXRARXRBRXRGCYP2C8 | |
| SCHEMBL1042428 | 0.78 | SRD5A2 (0.83) | SRD5A2RXRARXRBRXRGCYP2C8 | |
| SCHEMBL6762584 | 0.78 | SRD5A2 (0.83) | SRD5A2RXRARXRBRXRGCYP2C8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7223791-B2 | Function regulator for retinoid relative receptor | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2007-05-29 | — | — | US | disclosed |
| US-20040157881-A1 | Function regulator for retinoid relative receptor | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2004-08-12 | — | — | US | disclosed |
| EP-1405636-A1 | FUNCTION REGULATOR FOR RETINOID RELATIVE RECEPTOR | Takeda Chemical Industries, Ltd. (JP) | 2004-04-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040157881-A1 | Function regulator for retinoid relative receptor | RXRA, RARA, RARG | SRD5A2 323/4885RXRA 1/4885RXRB 6/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.