Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.40 |
| ▸ | ADCY8 | P40145 | 1/20 | 0.40 |
| ▸ | ADCY1 | Q08828 | 1/20 | 0.40 |
| ▸ | CCR2 | P41597 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | VCP | P55072 | 1/20 | 0.39 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.39 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.38 |
| ▸ | KMO | O15229 | 1/20 | 0.37 |
| ▸ | KCNJ6 | P48051 | 1/20 | 0.37 |
| ▸ | KCNJ5 | P48544 | 1/20 | 0.37 |
| ▸ | KCNJ3 | P48549 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5206605 | 0.88 | KCNH2 (0.51) | KCNH2CCR2VCPKMT2A | |
| SCHEMBL5206782 | 0.84 | FAAH (0.47) | ADORA1KCNH2ALDH1A1VCPITGB3 | |
| SCHEMBL5207759 | 0.81 | ADORA1 (0.43) | ADORA1KCNH2ALDH1A1VCPITGB3 | |
| SCHEMBL5210647 | 0.79 | TRPV3 (0.46) | ADORA1KCNH2ALDH1A1CNR2MEN1 | |
| SCHEMBL5205435 | 0.77 | KMO (0.41) | ADORA1ALDH1A1VCPITGB3ITGA2B | |
| SCHEMBL5207674 | 0.77 | PDE2A (0.39) | ADORA1ALDH1A1VCPKMO | |
| SCHEMBL14608992 | 0.77 | KCNH2 (0.47) | KCNH2ALDH1A1VCPMEN1POLB | |
| SCHEMBL5206565 | 0.77 | KCNH2 (0.47) | KCNH2ALDH1A1VCPMEN1POLB | |
| SCHEMBL5205158 | 0.77 | KCNH2 (0.47) | KCNH2ALDH1A1VCPMEN1POLB | |
| SCHEMBL5208528 | 0.76 | POLB (0.41) | ADORA1KCNH2ALDH1A1ITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1306085-B1 | 2-Cyclohexyl-4-phenyl-1H-imidazole derivatives as ligands for the neuropeptide Y5 receptor | NEUROGEN CORP (US) | 2007-02-14 | — | — | EP | claimed |