Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.40 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.39 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.38 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | KDM1A | O60341 | 2/20 | 0.37 |
| ▸ | MAOA | P21397 | 2/20 | 0.37 |
| ▸ | MAOB | P27338 | 2/20 | 0.37 |
| ▸ | KMO | O15229 | 2/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.36 |
| ▸ | GPR142 | Q7Z601 | 2/20 | 0.36 |
| ▸ | SOS1 | Q07889 | 2/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5210403 | 0.87 | SOS1 (0.45) | POLBMEN1ALDH1A1KMT2AUCHL1 | |
| SCHEMBL5205435 | 0.82 | KMO (0.41) | POLBMEN1ALDH1A1KMT2AADORA1 | |
| SCHEMBL5210647 | 0.80 | TRPV3 (0.46) | POLBMEN1ALDH1A1KMT2AADORA1 | |
| SCHEMBL5207759 | 0.79 | ADORA1 (0.43) | POLBMEN1ALDH1A1KMT2AADORA1 | |
| SCHEMBL5206782 | 0.78 | FAAH (0.47) | ALDH1A1ADORA1ITGB3ITGA2BRAB9A | |
| SCHEMBL5207845 | 0.76 | ADORA1 (0.41) | POLBMEN1ALDH1A1KMT2AADORA1 | |
| SCHEMBL5206565 | 0.76 | KCNH2 (0.47) | POLBMEN1ALDH1A1KMT2ARAB9A | |
| SCHEMBL14608992 | 0.76 | KCNH2 (0.47) | POLBMEN1ALDH1A1KMT2ARAB9A | |
| SCHEMBL5205158 | 0.76 | KCNH2 (0.47) | POLBMEN1ALDH1A1KMT2ARAB9A | |
| SCHEMBL312676 | 0.74 | KMO (0.44) | POLBMEN1ALDH1A1KMT2AADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1306085-B1 | 2-Cyclohexyl-4-phenyl-1H-imidazole derivatives as ligands for the neuropeptide Y5 receptor | NEUROGEN CORP (US) | 2007-02-14 | — | — | EP | claimed |