Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.32 |
| ▸ | SENP1 | Q9P0U3 | 1/20 | 0.30 |
| ▸ | F2 | P00734 | 1/20 | 0.30 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.30 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.30 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL5210732 | 0.85 | MAPT (0.35) | MAPTFOLH1LMNATP53HTT | |
| Trifluoroacetic Acid SCHEMBL5207834 | 0.82 | PDE4D (0.41) | MAPTLMNATP53 | |
| Trifluoroacetic Acid SCHEMBL5208832 | 0.81 | OPRM1 (0.35) | MAPTFOLH1LMNATP53HTT | |
| Trifluoroacetic Acid SCHEMBL5209515 | 0.80 | MAPT (0.40) | MAPTFOLH1LMNATP53HTT | |
| Trifluoroacetic Acid SCHEMBL5206475 | 0.80 | PTGER4 (0.34) | MAPTLMNATP53POLB | |
| Trifluoroacetic Acid SCHEMBL5210556 | 0.80 | CXCR2 (0.43) | LMNA | |
| Trifluoroacetic Acid SCHEMBL5207793 | 0.80 | PDE4D (0.40) | MAPTLMNATP53 | |
| Trifluoroacetic Acid SCHEMBL5208680 | 0.79 | KDM4E (0.36) | MAPTFOLH1LMNATP53HTT | |
| Trifluoroacetic Acid SCHEMBL5206983 | 0.79 | MAPT (0.41) | MAPTLMNATP53HTTPOLB | |
| Trifluoroacetic Acid SCHEMBL5217152 | 0.79 | ALDH1A1 (0.37) | MAPTLMNATP53HTTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1343561-B1 | SERINE PROTEASE INHIBITORS | TULARIK LTD (GB) | 2007-02-28 | — | — | EP | disclosed |