Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 4/20 | 0.34 |
| ▸ | F10 | P00742 | 1/20 | 0.32 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5204891 | 0.90 | KMT2A (0.33) | F2F10ADRA2CMEN1POLB | |
| Trifluoroacetic Acid SCHEMBL5629214 | 0.82 | F2 (0.32) | F2F10ADRA2C | |
| SCHEMBL5208588 | 0.80 | F2 (0.34) | F2F10ADRA2C | |
| Trifluoroacetic Acid SCHEMBL5210666 | 0.80 | OPRM1 (0.31) | F2 | |
| Trifluoroacetic Acid SCHEMBL5626916 | 0.79 | HDAC11 (0.32) | F2 | |
| Trifluoroacetic Acid SCHEMBL5626942 | 0.79 | FOLH1 (0.33) | F2F10 | |
| Trifluoroacetic Acid SCHEMBL5627045 | 0.79 | FOLH1 (0.39) | F2F10 | |
| Trifluoroacetic Acid SCHEMBL5631027 | 0.77 | F11 (0.32) | F10MEN1KMT2A | |
| SCHEMBL5628892 | 0.76 | ADRA2C (0.35) | F2F10ADRA2CKMT2A | |
| SCHEMBL5626868 | 0.76 | GLS (0.36) | F2F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1343561-B1 | SERINE PROTEASE INHIBITORS | TULARIK LTD (GB) | 2007-02-28 | — | — | EP | disclosed |